The BRCA2 R2645G variant increases DNA binding and induces hyper-recombination.
Alvaro-Aranda L, Petitalot A, Djeghmoum Y, Panigada D, Singh JK, Ehlén Å, Vugic D, Martin C, Miron S, Contreras-Perez A, Nhiri N, Boucherit V, Lafitte P, Dumoulin I, Quiles F, Rouleau E, Jacquet E, Feliubadaló L, Del Valle J, Sharan SK, Stoppa-Lyonnet D, Zinn-Justin S, Lázaro C, Caputo SM, Carreira A.
Alvaro-Aranda L, et al. Among authors: jacquet e.
Nucleic Acids Res. 2024 Jul 8;52(12):6964-6976. doi: 10.1093/nar/gkad1222.
Nucleic Acids Res. 2024.
PMID: 38142462
Free PMC article.