Xia D - Search Results

1

Identification of two novel heterodimeric ABC transporters in melanoma: ABCB5β/B6 and ABCB5β/B9.

Gerard L, Duvivier L, Fourrez M, Salazar P, Sprimont L, Xia D, Ambudkar SV, Gottesman MM, Gillet JP. Gerard L, et al. Among authors: xia d. J Biol Chem. 2024 Feb;300(2):105594. doi: 10.1016/j.jbc.2023.105594. Epub 2023 Dec 23. J Biol Chem. 2024. PMID: 38145744 Free PMC article.

2

Crystal structure of the heterodimeric complex of the adaptor, ClpS, with the N-domain of the AAA+ chaperone, ClpA.

Guo F, Esser L, Singh SK, Maurizi MR, Xia D. Guo F, et al. Among authors: xia d. J Biol Chem. 2002 Nov 29;277(48):46753-62. doi: 10.1074/jbc.M208104200. Epub 2002 Sep 15. J Biol Chem. 2002. PMID: 12235156 Free article.

3

The A-loop, a novel conserved aromatic acid subdomain upstream of the Walker A motif in ABC transporters, is critical for ATP binding.

Ambudkar SV, Kim IW, Xia D, Sauna ZE. Ambudkar SV, et al. Among authors: xia d. FEBS Lett. 2006 Feb 13;580(4):1049-55. doi: 10.1016/j.febslet.2005.12.051. Epub 2005 Dec 22. FEBS Lett. 2006. PMID: 16412422 Free article. Review.

4

The conserved tyrosine residues 401 and 1044 in ATP sites of human P-glycoprotein are critical for ATP binding and hydrolysis: evidence for a conserved subdomain, the A-loop in the ATP-binding cassette.

Kim IW, Peng XH, Sauna ZE, FitzGerald PC, Xia D, Müller M, Nandigama K, Ambudkar SV. Kim IW, et al. Among authors: xia d. Biochemistry. 2006 Jun 20;45(24):7605-16. doi: 10.1021/bi060308o. Biochemistry. 2006. PMID: 16768456

5

Defeating drug resistance in cancer.

Gottesman MM, Ludwig J, Xia D, Szakács G. Gottesman MM, et al. Among authors: xia d. Discov Med. 2006 Feb;6(31):18-23. Discov Med. 2006. PMID: 17234123 Free article.

6

Mutations define cross-talk between the N-terminal nucleotide-binding domain and transmembrane helix-2 of the yeast multidrug transporter Pdr5: possible conservation of a signaling interface for coupling ATP hydrolysis to drug transport.

Sauna ZE, Bohn SS, Rutledge R, Dougherty MP, Cronin S, May L, Xia D, Ambudkar SV, Golin J. Sauna ZE, et al. Among authors: xia d. J Biol Chem. 2008 Dec 12;283(50):35010-22. doi: 10.1074/jbc.M806446200. Epub 2008 Oct 8. J Biol Chem. 2008. PMID: 18842589 Free PMC article.

7

Structure of a multidrug transporter.

Gottesman MM, Ambudkar SV, Xia D. Gottesman MM, et al. Among authors: xia d. Nat Biotechnol. 2009 Jun;27(6):546-7. doi: 10.1038/nbt0609-546. Nat Biotechnol. 2009. PMID: 19513059 Free PMC article. No abstract available.

8

The signaling interface of the yeast multidrug transporter Pdr5 adopts a cis conformation, and there are functional overlap and equivalence of the deviant and canonical Q-loop residues.

Ananthaswamy N, Rutledge R, Sauna ZE, Ambudkar SV, Dine E, Nelson E, Xia D, Golin J. Ananthaswamy N, et al. Among authors: xia d. Biochemistry. 2010 Jun 1;49(21):4440-9. doi: 10.1021/bi100394j. Biochemistry. 2010. PMID: 20426485 Free PMC article.

9

Elevated expression of TMEM205, a hypothetical membrane protein, is associated with cisplatin resistance.

Shen DW, Ma J, Okabe M, Zhang G, Xia D, Gottesman MM. Shen DW, et al. Among authors: xia d. J Cell Physiol. 2010 Nov;225(3):822-8. doi: 10.1002/jcp.22287. J Cell Physiol. 2010. PMID: 20589834 Free PMC article.

10

Recognition of mesothelin by the therapeutic antibody MORAb-009: structural and mechanistic insights.

Ma J, Tang WK, Esser L, Pastan I, Xia D. Ma J, et al. Among authors: xia d. J Biol Chem. 2012 Sep 28;287(40):33123-31. doi: 10.1074/jbc.M112.381756. Epub 2012 Jul 11. J Biol Chem. 2012. PMID: 22787150 Free PMC article.

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