Gabr MT - Search Results

1

Discovery of Quinolinone Hybrids as Dual Inhibitors of Acetylcholinesterase and Aβ Aggregation for Alzheimer's Disease Therapy.

Manzoor S, Gabr MT, Nafie MS, Raza MK, Khan A, Nayeem SM, Arafa RK, Hoda N. Manzoor S, et al. Among authors: gabr mt. ACS Chem Neurosci. 2024 Feb 7;15(3):539-559. doi: 10.1021/acschemneuro.3c00588. Epub 2023 Dec 27. ACS Chem Neurosci. 2024. PMID: 38149821

2

Dual Targeting of Monomeric Tau and α-Synuclein Aggregation: A New Multitarget Therapeutic Strategy for Neurodegeneration.

Gabr MT, Peccati F. Gabr MT, et al. ACS Chem Neurosci. 2020 Jul 15;11(14):2051-2057. doi: 10.1021/acschemneuro.0c00281. Epub 2020 Jun 29. ACS Chem Neurosci. 2020. PMID: 32579329

3

Discovery of new phenyl sulfonyl-pyrimidine carboxylate derivatives as the potential multi-target drugs with effective anti-Alzheimer's action: Design, synthesis, crystal structure and in-vitro biological evaluation.

Manzoor S, Prajapati SK, Majumdar S, Raza MK, Gabr MT, Kumar S, Pal K, Rashid H, Kumar S, Krishnamurthy S, Hoda N. Manzoor S, et al. Among authors: gabr mt. Eur J Med Chem. 2021 Apr 5;215:113224. doi: 10.1016/j.ejmech.2021.113224. Epub 2021 Feb 2. Eur J Med Chem. 2021. PMID: 33582578

4

Dual targeting of acetylcholinesterase and tau aggregation: Design, synthesis and evaluation of multifunctional deoxyvasicinone analogues for Alzheimer's disease.

Manzoor S, Gabr MT, Rasool B, Pal K, Hoda N. Manzoor S, et al. Among authors: gabr mt. Bioorg Chem. 2021 Nov;116:105354. doi: 10.1016/j.bioorg.2021.105354. Epub 2021 Sep 11. Bioorg Chem. 2021. PMID: 34562674

5

Discovery of Hydroxybenzothiazole Urea Compounds as Multitargeted Agents Suppressing Major Cytotoxic Mechanisms in Neurodegenerative Diseases.

Aboushady Y, Gabr M, ElHady AK, Salah M, Abadi AH, Wilms G, Becker W, Abdel-Halim M, Engel M. Aboushady Y, et al. ACS Chem Neurosci. 2021 Nov 17;12(22):4302-4318. doi: 10.1021/acschemneuro.1c00475. Epub 2021 Nov 2. ACS Chem Neurosci. 2021. PMID: 34726394

6

Multicomponent Petasis reaction for the identification of pyrazine based multi-target directed anti-Alzheimer's agents: In-silico design, synthesis, and characterization.

Madhav H, Abdel-Rahman SA, Hashmi MA, Rahman MA, Rehan M, Pal K, Nayeem SM, Gabr MT, Hoda N. Madhav H, et al. Among authors: gabr mt. Eur J Med Chem. 2023 Jun 5;254:115354. doi: 10.1016/j.ejmech.2023.115354. Epub 2023 Apr 9. Eur J Med Chem. 2023. PMID: 37043996

7

Discovery of First-in-Class Small Molecule Inhibitors of Lymphocyte Activation Gene 3 (LAG-3).

Abdel-Rahman SA, Rehman AU, Gabr MT. Abdel-Rahman SA, et al. Among authors: gabr mt. ACS Med Chem Lett. 2023 Apr 11;14(5):629-635. doi: 10.1021/acsmedchemlett.3c00054. eCollection 2023 May 11. ACS Med Chem Lett. 2023. PMID: 37197466 Free PMC article.

8

MicroRNA-Based Multitarget Approach for Alzheimer's Disease: Discovery of the First-In-Class Dual Inhibitor of Acetylcholinesterase and MicroRNA-15b Biogenesis.

Gabr MT, Brogi S. Gabr MT, et al. J Med Chem. 2020 Sep 10;63(17):9695-9704. doi: 10.1021/acs.jmedchem.0c00756. Epub 2020 Aug 6. J Med Chem. 2020. PMID: 32787143

9

Discovery and Optimization of Small-Molecule Ligands for V-Domain Ig Suppressor of T-Cell Activation (VISTA).

Gabr MT, Gambhir SS. Gabr MT, et al. J Am Chem Soc. 2020 Sep 23;142(38):16194-16198. doi: 10.1021/jacs.0c07276. Epub 2020 Sep 10. J Am Chem Soc. 2020. PMID: 32894020

10

Discovery of Small-Molecule TIM-3 Inhibitors for Acute Myeloid Leukemia Using Pharmacophore-Based Virtual Screening.

Abdel-Rahman SA, Talagayev V, Pach S, Wolber G, Gabr MT. Abdel-Rahman SA, et al. Among authors: gabr mt. J Med Chem. 2023 Aug 24;66(16):11464-11475. doi: 10.1021/acs.jmedchem.3c00960. Epub 2023 Aug 11. J Med Chem. 2023. PMID: 37566998

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

56 results

Search Page

Filters