Boshta NM - Search Results

1

Design, synthesis, molecular docking and biological evaluation of 1,3,5-trisubstituted-1H-pyrazole derivatives as anticancer agents with cell cycle arrest, ERK and RIPK3- kinase activities.

Boshta NM, Temirak A, El-Shahid ZA, Shafiq Z, Soliman AAF. Boshta NM, et al. Bioorg Chem. 2024 Feb;143:107058. doi: 10.1016/j.bioorg.2023.107058. Epub 2023 Dec 28. Bioorg Chem. 2024. PMID: 38159496

2

Synthesis of the chromone-thiosemicarbazone scaffold as promising α-glucosidase inhibitors: An in vitro and in silico approach toward antidiabetic drug design.

Alharthy RD, Khalid S, Fatima S, Ullah S, Khan A, Mali SN, Jawarkar RD, Dhabarde SS, Kashtoh H, Taslimi P, Al-Harrasi A, Shafiq Z, Boshta NM. Alharthy RD, et al. Among authors: boshta nm. Arch Pharm (Weinheim). 2024 Aug;357(8):e2400140. doi: 10.1002/ardp.202400140. Epub 2024 Apr 30. Arch Pharm (Weinheim). 2024. PMID: 38687119

3

Synthesis, biological evaluation, and molecular modelling of substituted thiazolyl thiourea derivatives: A new class of prolyl oligopeptidase inhibitors.

Naseem S, Oneto A, Ullah S, Fatima S, Mali SN, Jawarkar RD, Khan A, Alharthy RD, Kashtoh H, Al-Harrasi A, Shafiq Z, Boshta NM. Naseem S, et al. Among authors: boshta nm. Int J Biol Macromol. 2024 Aug;275(Pt 1):133571. doi: 10.1016/j.ijbiomac.2024.133571. Epub 2024 Jul 1. Int J Biol Macromol. 2024. PMID: 38960243

4

Discovery of Quinazoline-2,4(1H,3H)-Dione Derivatives as Potential Antibacterial Agent: Design, Synthesis, and Their Antibacterial Activity.

Boshta NM, El-Essawy FA, Alshammari MB, Noreldein SG, Darwesh OM. Boshta NM, et al. Molecules. 2022 Jun 15;27(12):3853. doi: 10.3390/molecules27123853. Molecules. 2022. PMID: 35744976 Free PMC article.

5

Discovery of potent nucleotide pyrophosphatase/phosphodiesterase3 (NPP3) inhibitors with ancillary carbonic anhydrase inhibition for cancer (immuno)therapy.

Lee SY, Namasivayam V, Boshta NM, Perotti A, Mirza S, Bua S, Supuran CT, Müller CE. Lee SY, et al. Among authors: boshta nm. RSC Med Chem. 2021 Jun 16;12(7):1187-1206. doi: 10.1039/d1md00117e. eCollection 2021 Jul 21. RSC Med Chem. 2021. PMID: 34355184 Free PMC article.

6

Rapid and efficient synthesis of 4-substituted pyrazol-5-one under microwave irradiation in solvent-free conditions.

Zahran MA, El-Essawy FA, Yassin SM, Salem TA, Boshta NM. Zahran MA, et al. Among authors: boshta nm. Arch Pharm (Weinheim). 2007 Nov;340(11):591-8. doi: 10.1002/ardp.200700121. Arch Pharm (Weinheim). 2007. PMID: 17924363

7

Discovery of Anthranilic Acid Derivatives as Antagonists of the Pro-Inflammatory Orphan G Protein-Coupled Receptor GPR17.

Boshta NM, Lewash M, Köse M, Namasivayam V, Sarkar S, Voss JH, Liedtke AJ, Junker A, Tian M, Stößel A, Rashed M, Mahal A, Merten N, Pegurier C, Hockemeyer J, Kostenis E, Müller CE. Boshta NM, et al. J Med Chem. 2024 Nov 14;67(21):19365-19394. doi: 10.1021/acs.jmedchem.4c01755. Epub 2024 Nov 1. J Med Chem. 2024. PMID: 39484825

8

Potent, Selective Agonists for the Cannabinoid-like Orphan G Protein-Coupled Receptor GPR18: A Promising Drug Target for Cancer and Immunity.

Mahardhika AB, Załuski M, Schoeder CT, Boshta NM, Schabikowski J, Perri F, Łażewska D, Neumann A, Kremers S, Oneto A, Ressemann A, Latacz G, Namasivayam V, Kieć-Kononowicz K, Müller CE. Mahardhika AB, et al. Among authors: boshta nm. J Med Chem. 2024 Jun 27;67(12):9896-9926. doi: 10.1021/acs.jmedchem.3c02423. Epub 2024 Jun 17. J Med Chem. 2024. PMID: 38885438

9

Stereoselective formation of triphenylene ketals.

Boshta NM, Bomkamp M, Schnakenburg G, Waldvogel SR. Boshta NM, et al. Chemistry. 2010 Mar 15;16(11):3459-66. doi: 10.1002/chem.200903249. Chemistry. 2010. PMID: 20157907

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