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Page 1
Quantitative proteomic mass spectrometry of protein kinases to determine dynamic heterogeneity of the human kinome.
East MP, Sprung RW, Okumu DO, Olivares-Quintero JF, Joisa CU, Chen X, Zhang Q, Erdmann-Gilmore P, Mi Y, Sciaky N, Malone JP, Bhatia S, McCabe IC, Xu Y, Sutcliffe MD, Luo J, Spears PA, Perou CM, Earp HS, Carey LA, Yeh JJ, Spector DL, Gomez SM, Spanheimer PM, Townsend RR, Johnson GL. East MP, et al. Among authors: okumu do. bioRxiv [Preprint]. 2024 Oct 4:2024.10.04.614143. doi: 10.1101/2024.10.04.614143. bioRxiv. 2024. PMID: 39464086 Free PMC article. Preprint.
Combined kinome inhibition states are predictive of cancer cell line sensitivity to kinase inhibitor combination therapies.
Joisa CU, Chen KA, Beville S, Stuhlmiller T, Berginski ME, Okumu D, Golitz BT, Johnson GL, Gomez SM. Joisa CU, et al. Among authors: okumu d. bioRxiv [Preprint]. 2023 Aug 3:2023.08.01.551346. doi: 10.1101/2023.08.01.551346. bioRxiv. 2023. Update in: Pac Symp Biocomput. 2024;29:276-290. PMID: 37577663 Free PMC article. Updated. Preprint.
Lyn regulates creatine uptake in an imatinib-resistant CML cell line.
Okumu DO, Aponte-Collazo LJ, Dewar BJ, Cox NJ, East MP, Tech K, McDonald IM, Tikunov AP, Holmuhamedov E, Macdonald JM, Graves LM. Okumu DO, et al. Biochim Biophys Acta Gen Subj. 2020 Apr;1864(4):129507. doi: 10.1016/j.bbagen.2019.129507. Epub 2019 Dec 24. Biochim Biophys Acta Gen Subj. 2020. PMID: 31881245 Free PMC article.
Application of Integrated Drug Screening/Kinome Analysis to Identify Inhibitors of Gemcitabine-Resistant Pancreatic Cancer Cell Growth.
Krulikas LJ, McDonald IM, Lee B, Okumu DO, East MP, Gilbert TSK, Herring LE, Golitz BT, Wells CI, Axtman AD, Zuercher WJ, Willson TM, Kireev D, Yeh JJ, Johnson GL, Baines AT, Graves LM. Krulikas LJ, et al. Among authors: okumu do. SLAS Discov. 2018 Sep;23(8):850-861. doi: 10.1177/2472555218773045. Epub 2018 May 9. SLAS Discov. 2018. PMID: 29742358 Free PMC article.
BIRC6 mediates imatinib resistance independently of Mcl-1.
Okumu DO, East MP, Levine M, Herring LE, Zhang R, Gilbert TSK, Litchfield DW, Zhang Y, Graves LM. Okumu DO, et al. PLoS One. 2017 May 16;12(5):e0177871. doi: 10.1371/journal.pone.0177871. eCollection 2017. PLoS One. 2017. PMID: 28520795 Free PMC article.