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Page 1
Acute myeloid leukemia stratifies as 2 clinically relevant sphingolipidomic subtypes.
Paudel BB, Tan SF, Fox TE, Ung J, Golla U, Shaw JJP, Dunton W, Lee I, Fares WA, Patel S, Sharma A, Viny AD, Barth BM, Tallman MS, Cabot M, Garrett-Bakelman FE, Levine RL, Kester M, Feith DJ, Claxton D, Janes KA, Loughran TP Jr. Paudel BB, et al. Among authors: shaw jjp. Blood Adv. 2024 Mar 12;8(5):1137-1142. doi: 10.1182/bloodadvances.2023010535. Blood Adv. 2024. PMID: 38170742 Free PMC article. No abstract available.
Simultaneous Inhibition of Ceramide Hydrolysis and Glycosylation Synergizes to Corrupt Mitochondrial Respiration and Signal Caspase Driven Cell Death in Drug-Resistant Acute Myeloid Leukemia.
Fisher-Wellman KH, Kassai M, Hagen JT, Neufer PD, Kester M, Loughran TP Jr, Chalfant CE, Feith DJ, Tan SF, Fox TE, Ung J, Fabrias G, Abad JL, Sharma A, Golla U, Claxton DF, Shaw JJP, Bhowmick D, Cabot MC. Fisher-Wellman KH, et al. Among authors: shaw jjp. Cancers (Basel). 2023 Mar 21;15(6):1883. doi: 10.3390/cancers15061883. Cancers (Basel). 2023. PMID: 36980769 Free PMC article.
Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia.
Ung J, Tan SF, Fox TE, Shaw JJ, Taori M, Horton BJ, Golla U, Sharma A, Szulc ZM, Wang HG, Chalfant CE, Cabot MC, Claxton DF, Loughran TP, Feith DJ. Ung J, et al. bioRxiv [Preprint]. 2023 Oct 23:2023.10.21.563437. doi: 10.1101/2023.10.21.563437. bioRxiv. 2023. Update in: Cancers (Basel). 2023 Dec 15;15(24):5866. doi: 10.3390/cancers15245866 PMID: 37961314 Free PMC article. Updated. Preprint.
The interaction between RIPK1 and FADD controls perinatal lethality and inflammation.
Rodriguez DA, Tummers B, Shaw JJP, Quarato G, Weinlich R, Cripps J, Fitzgerald P, Janke LJ, Pelletier S, Crawford JC, Green DR. Rodriguez DA, et al. Among authors: shaw jjp. Cell Rep. 2024 Jun 25;43(6):114335. doi: 10.1016/j.celrep.2024.114335. Epub 2024 Jun 8. Cell Rep. 2024. PMID: 38850531 Free PMC article.
Caspase-8 and FADD prevent spontaneous ZBP1 expression and necroptosis.
Rodriguez DA, Quarato G, Liedmann S, Tummers B, Zhang T, Guy C, Crawford JC, Palacios G, Pelletier S, Kalkavan H, Shaw JJP, Fitzgerald P, Chen MJ, Balachandran S, Green DR. Rodriguez DA, et al. Among authors: shaw jjp. Proc Natl Acad Sci U S A. 2022 Oct 11;119(41):e2207240119. doi: 10.1073/pnas.2207240119. Epub 2022 Oct 3. Proc Natl Acad Sci U S A. 2022. PMID: 36191211 Free PMC article.
Harnessing the power of sphingolipids: Prospects for acute myeloid leukemia.
Ung J, Tan SF, Fox TE, Shaw JJP, Vass LR, Costa-Pinheiro P, Garrett-Bakelman FE, Keng MK, Sharma A, Claxton DF, Levine RL, Tallman MS, Cabot MC, Kester M, Feith DJ, Loughran TP Jr. Ung J, et al. Among authors: shaw jjp. Blood Rev. 2022 Sep;55:100950. doi: 10.1016/j.blre.2022.100950. Epub 2022 Apr 9. Blood Rev. 2022. PMID: 35487785 Free PMC article. Review.
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