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Page 1
Heterogeneity of Myc expression in breast cancer exposes pharmacological vulnerabilities revealed through executable mechanistic modeling.
Kreuzaler P, Clarke MA, Brown EJ, Wilson CH, Kortlever RM, Piterman N, Littlewood T, Evan GI, Fisher J. Kreuzaler P, et al. Among authors: brown ej. Proc Natl Acad Sci U S A. 2019 Oct 29;116(44):22399-22408. doi: 10.1073/pnas.1903485116. Epub 2019 Oct 14. Proc Natl Acad Sci U S A. 2019. PMID: 31611367 Free PMC article.
Association of oropharyngeal cancer recurrence with tumor-intrinsic and immune-mediated sequelae of reduced genomic instability.
Sannigrahi MK, Raghav L, Rich DJ, Schrank TP, Califano JA, Lukens JN, Sun L, Morgan IM, Cohen RB, Lin A, Liu X, Brown EJ, You J, Mirabello L, Mishra SK, Shimunov D, Brody RM, Pearson AT, Gimotty PA, Diab A, Jalaly JB, Basu D. Sannigrahi MK, et al. Among authors: brown ej. bioRxiv [Preprint]. 2024 Nov 4:2024.10.31.621311. doi: 10.1101/2024.10.31.621311. bioRxiv. 2024. PMID: 39574723 Free PMC article. Preprint.
USP50 suppresses alternative RecQ helicase use and deleterious DNA2 activity during replication.
Mackay HL, Stone HR, Ronson GE, Ellis K, Lanz A, Aghabi Y, Walker AK, Starowicz K, Garvin AJ, Van Eijk P, Koestler SA, Anthony EJ, Piberger AL, Chauhan AS, Conway-Thomas P, Vaitsiankova A, Vijayendran S, Beesley JF, Petermann E, Brown EJ, Densham RM, Reed SH, Dobbs F, Saponaro M, Morris JR. Mackay HL, et al. Among authors: brown ej. Nat Commun. 2024 Sep 16;15(1):8102. doi: 10.1038/s41467-024-52250-4. Nat Commun. 2024. PMID: 39284827 Free PMC article.
Improved detection of DNA replication fork-associated proteins.
Rivard RS, Chang YC, Ragland RL, Thu YM, Kassab M, Mandal RS, Van Riper SK, Kulej K, Higgins L, Markowski TM, Shang D, Hedberg J, Erber L, Garcia B, Chen Y, Bielinsky AK, Brown EJ. Rivard RS, et al. Among authors: brown ej. Cell Rep. 2024 May 28;43(5):114178. doi: 10.1016/j.celrep.2024.114178. Epub 2024 May 2. Cell Rep. 2024. PMID: 38703364 Free article.
USP50 suppresses alternative RecQ helicase use and deleterious DNA2 activity during replication.
Mackay HL, Stone HR, Ellis K, Ronson GE, Walker AK, Starowicz K, Garvin AJ, van Eijk P, Vaitsiankova A, Vijayendran S, Beesley JF, Petermann E, Brown EJ, Densham RM, Reed SH, Dobbs F, Saponaro M, Morris JR. Mackay HL, et al. Among authors: brown ej. bioRxiv [Preprint]. 2024 Jan 11:2024.01.10.574674. doi: 10.1101/2024.01.10.574674. bioRxiv. 2024. Update in: Nat Commun. 2024 Sep 16;15(1):8102. doi: 10.1038/s41467-024-52250-4 PMID: 38260523 Free PMC article. Updated. Preprint.
522 results