Mi H - Search Results

1

Spatial and Compositional Biomarkers in Tumor Microenvironment Predicts Clinical Outcomes in Triple-Negative Breast Cancer.

Mi H, Varadhan R, Cimino-Mathews AM, Emens LA, Santa-Maria CA, Popel AS. Mi H, et al. bioRxiv [Preprint]. 2023 Dec 20:2023.12.18.572234. doi: 10.1101/2023.12.18.572234. bioRxiv. 2023. Update in: Mod Pathol. 2024 Nov 8;38(2):100652. doi: 10.1016/j.modpat.2024.100652 PMID: 38187696 Free PMC article. Updated. Preprint.

2

Digital Pathology Analysis Quantifies Spatial Heterogeneity of CD3, CD4, CD8, CD20, and FoxP3 Immune Markers in Triple-Negative Breast Cancer.

Mi H, Gong C, Sulam J, Fertig EJ, Szalay AS, Jaffee EM, Stearns V, Emens LA, Cimino-Mathews AM, Popel AS. Mi H, et al. Front Physiol. 2020 Oct 19;11:583333. doi: 10.3389/fphys.2020.583333. eCollection 2020. Front Physiol. 2020. PMID: 33192595 Free PMC article.

3

Predictive models of response to neoadjuvant chemotherapy in muscle-invasive bladder cancer using nuclear morphology and tissue architecture.

Mi H, Bivalacqua TJ, Kates M, Seiler R, Black PC, Popel AS, Baras AS. Mi H, et al. Cell Rep Med. 2021 Aug 27;2(9):100382. doi: 10.1016/j.xcrm.2021.100382. eCollection 2021 Sep 21. Cell Rep Med. 2021. PMID: 34622225 Free PMC article.

4

Multi-Scale Spatial Analysis of the Tumor Microenvironment Reveals Features of Cabozantinib and Nivolumab Efficacy in Hepatocellular Carcinoma.

Mi H, Ho WJ, Yarchoan M, Popel AS. Mi H, et al. Front Immunol. 2022 May 13;13:892250. doi: 10.3389/fimmu.2022.892250. eCollection 2022. Front Immunol. 2022. PMID: 35634309 Free PMC article.

5

Simulations of tumor growth and response to immunotherapy by coupling a spatial agent-based model with a whole-patient quantitative systems pharmacology model.

Ruiz-Martinez A, Gong C, Wang H, Sové RJ, Mi H, Kimko H, Popel AS. Ruiz-Martinez A, et al. Among authors: mi h. PLoS Comput Biol. 2022 Jul 22;18(7):e1010254. doi: 10.1371/journal.pcbi.1010254. eCollection 2022 Jul. PLoS Comput Biol. 2022. PMID: 35867773 Free PMC article.

6

Quantitative Spatial Profiling of Immune Populations in Pancreatic Ductal Adenocarcinoma Reveals Tumor Microenvironment Heterogeneity and Prognostic Biomarkers.

Mi H, Sivagnanam S, Betts CB, Liudahl SM, Jaffee EM, Coussens LM, Popel AS. Mi H, et al. Cancer Res. 2022 Dec 2;82(23):4359-4372. doi: 10.1158/0008-5472.CAN-22-1190. Cancer Res. 2022. PMID: 36112643 Free PMC article.

7

Quantifying Intratumoral Heterogeneity and Immunoarchitecture Generated In-Silico by a Spatial Quantitative Systems Pharmacology Model.

Nikfar M, Mi H, Gong C, Kimko H, Popel AS. Nikfar M, et al. Among authors: mi h. Cancers (Basel). 2023 May 13;15(10):2750. doi: 10.3390/cancers15102750. Cancers (Basel). 2023. PMID: 37345087 Free PMC article.

8

Informing virtual clinical trials of hepatocellular carcinoma with spatial multi-omics analysis of a human neoadjuvant immunotherapy clinical trial.

Zhang S, Deshpande A, Verma BK, Wang H, Mi H, Yuan L, Ho WJ, Jaffee EM, Zhu Q, Anders RA, Yarchoan M, Kagohara LT, Fertig EJ, Popel AS. Zhang S, et al. Among authors: mi h. bioRxiv [Preprint]. 2023 Aug 15:2023.08.11.553000. doi: 10.1101/2023.08.11.553000. bioRxiv. 2023. PMID: 37645761 Free PMC article. Preprint.

9

Integration of Clinical Trial Spatial Multiomics Analysis and Virtual Clinical Trials Enables Immunotherapy Response Prediction and Biomarker Discovery.

Zhang S, Deshpande A, Verma BK, Wang H, Mi H, Yuan L, Ho WJ, Jaffee EM, Zhu Q, Anders RA, Yarchoan M, Kagohara LT, Fertig EJ, Popel AS. Zhang S, et al. Among authors: mi h. Cancer Res. 2024 Aug 15;84(16):2734-2748. doi: 10.1158/0008-5472.CAN-24-0943. Cancer Res. 2024. PMID: 38861365

10

Computational methods and biomarker discovery strategies for spatial proteomics: a review in immuno-oncology.

Mi H, Sivagnanam S, Ho WJ, Zhang S, Bergman D, Deshpande A, Baras AS, Jaffee EM, Coussens LM, Fertig EJ, Popel AS. Mi H, et al. Brief Bioinform. 2024 Jul 25;25(5):bbae421. doi: 10.1093/bib/bbae421. Brief Bioinform. 2024. PMID: 39179248 Free PMC article. Review.

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