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Anti-CELA1 antibody KF4 prevents emphysema by inhibiting stretch-mediated remodeling.
Ojha M, Smith NJ, Devine AJ, Joshi R, Goodman EM, Fan Q, Schuman R, Porollo A, Wells JM, Tiwary E, Batie MR, Gray J, Deshmukh H, Borchers MT, Ammerman SA, Varisco BM. Ojha M, et al. Among authors: smith nj. JCI Insight. 2024 Jan 9;9(1):e169189. doi: 10.1172/jci.insight.169189. JCI Insight. 2024. PMID: 38193533 Free PMC article.
KF4 anti-CELA1 Antibody and Purified α1-Antitrypsin Have Similar but Not Additive Efficacy in Preventing Emphysema in Murine α1-Antitrypsin Deficiency.
Devine AJ, Smith NJ, Joshi R, Brooks-Patton B, Dunham J, Varisco AN, Goodman EM, Fan Q, Zingarelli B, Varisco BM. Devine AJ, et al. Among authors: smith nj. bioRxiv [Preprint]. 2024 May 10:2024.05.07.592994. doi: 10.1101/2024.05.07.592994. bioRxiv. 2024. Update in: Chronic Obstr Pulm Dis. 2024 Nov 26. doi: 10.15326/jcopdf.2024.0535 PMID: 38766202 Free PMC article. Updated. Preprint.
KF4 Anti-Chymotrypsin-like Elastase 1 Antibody and Purified Alpha-1 Antitrypsin Have Similar but Not Additive Efficacy in Preventing Emphysema in Murine Alpha-1 Antitrypsin Deficiency.
Devine AJ, Smith NJ, Joshi R, Brooks-Patton B, Dunham J, Varisco AN, Goodman EM, Fan Q, Zingarelli B, Varisco BM. Devine AJ, et al. Among authors: smith nj. Chronic Obstr Pulm Dis. 2024 Nov 26. doi: 10.15326/jcopdf.2024.0535. Online ahead of print. Chronic Obstr Pulm Dis. 2024. PMID: 39636054 Free article.
Differentiation signals induce APOBEC3A expression via GRHL3 in squamous epithelia and squamous cell carcinoma.
Smith NJ, Reddin I, Policelli P, Oh S, Zainal N, Howes E, Jenkins B, Tracy I, Edmond M, Sharpe B, Amendra D, Zheng K, Egawa N, Doorbar J, Rao A, Mahadevan S, Carpenter MA, Harris RS, Ali S, Hanley C, Buisson R, King E, Thomas GJ, Fenton TR. Smith NJ, et al. EMBO J. 2025 Jan;44(1):1-29. doi: 10.1038/s44318-024-00298-9. Epub 2024 Nov 15. EMBO J. 2025. PMID: 39548236 Free PMC article.
419 results