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Transcriptomic signatures of individual cell types in cerebral cavernous malformation.
Li Y, Girard R, Srinath A, Cruz DV, Ciszewski C, Chen C, Lightle R, Romanos S, Sone JY, Moore T, DeBiasse D, Stadnik A, Lee JJ, Shenkar R, Koskimäki J, Lopez-Ramirez MA, Marchuk DA, Ginsberg MH, Kahn ML, Shi C, Awad IA. Li Y, et al. Among authors: chen c. Cell Commun Signal. 2024 Jan 9;22(1):23. doi: 10.1186/s12964-023-01301-2. Cell Commun Signal. 2024. PMID: 38195510 Free PMC article.
Circulating Plasma miRNA Homologs in Mice and Humans Reflect Familial Cerebral Cavernous Malformation Disease.
Romanos SG, Srinath A, Li Y, Xie B, Chen C, Li Y, Moore T, Bi D, Sone JY, Lightle R, Hobson N, Zhang D, Koskimäki J, Shen L, McCurdy S, Lai CC, Stadnik A, Piedad K, Carrión-Penagos J, Shkoukani A, Snellings D, Shenkar R, Sulakhe D, Ji Y, Lopez-Ramirez MA, Kahn ML, Marchuk DA, Ginsberg MH, Girard R, Awad IA. Romanos SG, et al. Among authors: chen c. Transl Stroke Res. 2023 Aug;14(4):513-529. doi: 10.1007/s12975-022-01050-3. Epub 2022 Jun 17. Transl Stroke Res. 2023. PMID: 35715588 Free PMC article.
Plasma metabolites with mechanistic and clinical links to the neurovascular disease cavernous angioma.
Srinath A, Xie B, Li Y, Sone JY, Romanos S, Chen C, Sharma A, Polster S, Dorrestein PC, Weldon KC, DeBiasse D, Moore T, Lightle R, Koskimäki J, Zhang D, Stadnik A, Piedad K, Hagan M, Shkoukani A, Carrión-Penagos J, Bi D, Shen L, Shenkar R, Ji Y, Sidebottom A, Pamer E, Gilbert JA, Kahn ML, D'Souza M, Sulakhe D, Awad IA, Girard R. Srinath A, et al. Among authors: chen c. Commun Med (Lond). 2023 Mar 3;3(1):35. doi: 10.1038/s43856-023-00265-1. Commun Med (Lond). 2023. PMID: 36869161 Free PMC article.
Perivascular cells function as key mediators of mechanical and structural changes in vascular capillaries.
Franca CM, Lima Verde ME, Silva-Sousa AC, Mansoorifar A, Athirasala A, Subbiah R, Tahayeri A, Sousa M, Fraga MA, Visalakshan RM, Doe A, Beadle K, Finley M, Dimitriadis E, Bays J, Uroz M, Yamada KM, Chen C, Bertassoni LE. Franca CM, et al. Among authors: chen c. Sci Adv. 2025 Jan 10;11(2):eadp3789. doi: 10.1126/sciadv.adp3789. Epub 2025 Jan 10. Sci Adv. 2025. PMID: 39792671
α-Ketoglutarate dehydrogenase is a therapeutic vulnerability in acute myeloid leukemia.
Millman SE, Chaves-Perez A, Janaki-Raman S, Ho YJ, Morris Iv JP, Narendra V, Chen CC, Jackson BT, Yashinskie JJ, Mezzadra R, Devine TI, Barthet VJA, Saoi M, Baslan T, Tian S, Sachs Z, Finley LW, Cross JR, Lowe SW. Millman SE, et al. Among authors: chen cc. Blood. 2024 Dec 27:blood.2024025245. doi: 10.1182/blood.2024025245. Online ahead of print. Blood. 2024. PMID: 39791576
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