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GZMK+CD8+ T cells Target A Specific Acinar Cell Type in Sjögren's Disease.
Pranzatelli TJF, Perez P, Ku A, Matuck B, Huynh K, Sakai S, Abed M, Jang SI, Yamada E, Dominick K, Ahmed Z, Oliver A, Wasikowski R, Easter QT, Baer AN, Pelayo E, Khavandgar Z, Kleiner DE, Magone MT, Gupta S, Lessard C, Farris AD, Burbelo PD, Martin D, Morell RJ, Zheng C, Rachmaninoff N, Maldonado-Ortiz J, Qu X, Aure M, Dezfulian MH, Lake R, Teichmann S, Barber DL, Tsoi LC, Sowalsky AG, Tyc KM, Liu J, Gudjonsson J, Byrd KM, Johnson PLF, Chiorini JA, Warner BM. Pranzatelli TJF, et al. Among authors: gupta s. Res Sq [Preprint]. 2024 Jul 11:rs.3.rs-3601404. doi: 10.21203/rs.3.rs-3601404/v1. Res Sq. 2024. PMID: 38196575 Free PMC article. Preprint.
Inhibition of JAK-STAT pathway corrects salivary gland inflammation and interferon driven immune activation in Sjögren's Disease.
Gupta S, Yamada E, Nakamura H, Perez P, Pranzatelli TJF, Dominick K, Jang SI, Abed M, Martin D, Burbelo P, Zheng C, French B, Alevizos I, Khavandgar Z, Beach M, Pelayo E, Walitt B, Hasni S, Kaplan MJ, Tandon M, Teresa Magone M, Kleiner DE, Chiorini JA, Baer AN, Warner BM. Gupta S, et al. medRxiv [Preprint]. 2023 Aug 21:2023.08.16.23294130. doi: 10.1101/2023.08.16.23294130. medRxiv. 2023. Update in: Ann Rheum Dis. 2024 Jul 15;83(8):1034-1047. doi: 10.1136/ard-2023-224842 PMID: 37662351 Free PMC article. Updated. Preprint.
Inhibition of JAK-STAT pathway corrects salivary gland inflammation and interferon driven immune activation in Sjögren's disease.
Gupta S, Yamada E, Nakamura H, Perez P, Pranzatelli TJ, Dominick K, Jang SI, Abed M, Martin D, Burbelo P, Zheng C, French B, Alevizos I, Khavandgar Z, Beach M, Pelayo E, Walitt B, Hasni S, Kaplan MJ, Tandon M, Magone MT, Kleiner DE, Chiorini JA, Baer A, Warner BM. Gupta S, et al. Ann Rheum Dis. 2024 Jul 15;83(8):1034-1047. doi: 10.1136/ard-2023-224842. Ann Rheum Dis. 2024. PMID: 38527764 Free PMC article.
The Aconitate Decarboxylase 1/Itaconate Pathway Modulates Immune Dysregulation and Associates with Cardiovascular Disease Markers and Disease Activity in Systemic Lupus Erythematosus.
Patiño-Martinez E, Nakabo S, Jiang K, Carmona-Rivera C, Tsai WL, Claybaugh D, Yu ZX, Romero A, Bohrnsen E, Schwarz B, Solís-Barbosa MA, Blanco LP, Naqi M, Temesgen-Oyelakin Y, Davis M, Manna Z, Gupta S, Mehta N, Naz F, dell'Orso S, Hasni S, Kaplan MJ. Patiño-Martinez E, et al. Among authors: gupta s. J Immunol. 2024 Aug 15;213(4):419-434. doi: 10.4049/jimmunol.2400241. J Immunol. 2024. PMID: 38949522
Leucine Aminopeptidase LyLAP enables lysosomal degradation of membrane proteins.
Jain A, Heremans I, Rademaker G, Detomasi TC, Hernandez GA, Zhang J, Gupta S, von Linde T, Lange M, Spacci M, Rohweder P, Anderson D, Citron YR, Olzmann JA, Dawson DW, Craik CS, Bommer G, Perera RM, Zoncu R. Jain A, et al. Among authors: gupta s. bioRxiv [Preprint]. 2024 Dec 14:2024.12.13.628212. doi: 10.1101/2024.12.13.628212. bioRxiv. 2024. PMID: 39713462 Free PMC article. Preprint.
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