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Adding α,α-disubstituted and β-linked monomers to the genetic code of an organism.
Nature. 2024 Jan;625(7995):603-610. doi: 10.1038/s41586-023-06897-6. Epub 2024 Jan 10.
Nature. 2024.
PMID: 38200312
Free PMC article.
Genetically programmed cell-based synthesis of non-natural peptide and depsipeptide macrocycles.
Spinck M, Piedrafita C, Robertson WE, Elliott TS, Cervettini D, de la Torre D, Chin JW.
Spinck M, et al. Among authors: cervettini d.
Nat Chem. 2023 Jan;15(1):61-69. doi: 10.1038/s41557-022-01082-0. Epub 2022 Dec 22.
Nat Chem. 2023.
PMID: 36550233
Free PMC article.
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Sense codon reassignment enables viral resistance and encoded polymer synthesis.
Robertson WE, Funke LFH, de la Torre D, Fredens J, Elliott TS, Spinck M, Christova Y, Cervettini D, Böge FL, Liu KC, Buse S, Maslen S, Salmond GPC, Chin JW.
Robertson WE, et al. Among authors: cervettini d.
Science. 2021 Jun 4;372(6546):1057-1062. doi: 10.1126/science.abg3029.
Science. 2021.
PMID: 34083482
Free PMC article.
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Rapid discovery and evolution of orthogonal aminoacyl-tRNA synthetase-tRNA pairs.
Cervettini D, Tang S, Fried SD, Willis JCW, Funke LFH, Colwell LJ, Chin JW.
Cervettini D, et al.
Nat Biotechnol. 2020 Aug;38(8):989-999. doi: 10.1038/s41587-020-0479-2. Epub 2020 Apr 13.
Nat Biotechnol. 2020.
PMID: 32284585
Free PMC article.
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