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KCNQ1 is an essential mediator of the sex-dependent perception of moderate cold temperatures.
Kiper AK, Wegner S, Kadala A, Rinné S, Schütte S, Winter Z, Bertoune MAR, Touska F, Matschke V, Wrobel E, Streit AK, Lang F, Schmidt C, Schulze-Bahr E, Schäfer MK, Voelkl J, Seebohm G, Zimmermann K, Decher N. Kiper AK, et al. Proc Natl Acad Sci U S A. 2024 Jun 18;121(25):e2322475121. doi: 10.1073/pnas.2322475121. Epub 2024 Jun 10. Proc Natl Acad Sci U S A. 2024. PMID: 38857404 Free PMC article.
Popeye domain containing proteins modulate the voltage-gated cardiac sodium channel Nav1.5.
Rinné S, Kiper AK, Jacob R, Ortiz-Bonnin B, Schindler RFR, Fischer S, Komadowski M, De Martino E, Schäfer MK, Cornelius T, Fabritz L, Helker CSM, Brand T, Decher N. Rinné S, et al. Among authors: kiper ak. iScience. 2024 Apr 9;27(5):109696. doi: 10.1016/j.isci.2024.109696. eCollection 2024 May 17. iScience. 2024. PMID: 38689644 Free PMC article.
Cloxyquin activates hTRESK by allosteric modulation of the selectivity filter.
Schreiber JA, Derksen A, Goerges G, Schütte S, Sörgel J, Kiper AK, Strutz-Seebohm N, Ruck T, Meuth SG, Decher N, Seebohm G. Schreiber JA, et al. Among authors: kiper ak. Commun Biol. 2023 Jul 18;6(1):745. doi: 10.1038/s42003-023-05114-4. Commun Biol. 2023. PMID: 37464013 Free PMC article.
Selective TASK-1 Inhibitor with a Defined Structure-Activity Relationship Reduces Cancer Cell Proliferation and Viability.
Arévalo B, Bedoya M, Kiper AK, Vergara F, Ramírez D, Mazola Y, Bustos D, Zúñiga R, Cikutovic R, Cayo A, Rinné S, Ramirez-Apan MT, Sepúlveda FV, Cerda O, López-Collazo E, Decher N, Zúñiga L, Gutierrez M, González W. Arévalo B, et al. Among authors: kiper ak. J Med Chem. 2022 Nov 24;65(22):15014-15027. doi: 10.1021/acs.jmedchem.1c00378. Epub 2022 Nov 15. J Med Chem. 2022. PMID: 36378530
44 results