Xu Q - Search Results

1

A mechanistic biomarker investigation of fialuridine hepatotoxicity using the chimeric TK-NOG Hu-liver mouse model and in vitro micropatterned hepatocyte cocultures.

Aslamkhan AG, Michna L, Podtelezhnikov A, Vlasakova K, Suemizu H, Ohnishi Y, Liu L, Lane P, Xu Q, Kuhls MC, Wang Z, Pacchione S, Erdos Z, Tracy RW, Koeplinger K, Muniappa N, Valentine J, Galijatovic-Idrizbegovic A, Glaab WE, Sistare FD, Lebron J. Aslamkhan AG, et al. Among authors: xu q. Toxicol Res (Camb). 2024 Jan 11;13(1):tfad120. doi: 10.1093/toxres/tfad120. eCollection 2024 Feb. Toxicol Res (Camb). 2024. PMID: 38223529

2

Can Galactose Be Converted to Glucose in HepG2 Cells? Improving the in Vitro Mitochondrial Toxicity Assay for the Assessment of Drug Induced Liver Injury.

Xu Q, Liu L, Vu H, Kuhls M, Aslamkhan AG, Liaw A, Yu Y, Kaczor A, Ruth M, Wei C, Imredy J, Lebron J, Pearson K, Gonzalez R, Mitra K, Sistare FD. Xu Q, et al. Chem Res Toxicol. 2019 Aug 19;32(8):1528-1544. doi: 10.1021/acs.chemrestox.9b00033. Epub 2019 Jul 18. Chem Res Toxicol. 2019. PMID: 31271030

3

Characterization of indoleamine-2,3-dioxygenase 1, tryptophan-2,3-dioxygenase, and Ido1/Tdo2 knockout mice.

Aslamkhan AG, Xu Q, Loughlin A, Vu H, Pacchione S, Bhatt B, Garfinkel I, Styring TG, LaFranco-Scheuch L, Pearson K, Reynolds S, Li N, Zhou H, Miller JR, Solban N, Bass A, Glaab WE. Aslamkhan AG, et al. Among authors: xu q. Toxicol Appl Pharmacol. 2020 Nov 1;406:115216. doi: 10.1016/j.taap.2020.115216. Epub 2020 Aug 29. Toxicol Appl Pharmacol. 2020. PMID: 32871117

4

Integrated pathway analysis of rat urine metabolic profiles and kidney transcriptomic profiles to elucidate the systems toxicology of model nephrotoxicants.

Xu EY, Perlina A, Vu H, Troth SP, Brennan RJ, Aslamkhan AG, Xu Q. Xu EY, et al. Among authors: xu q. Chem Res Toxicol. 2008 Aug;21(8):1548-61. doi: 10.1021/tx800061w. Epub 2008 Jul 26. Chem Res Toxicol. 2008. PMID: 18656965

5

Magnetic Resonance and Ultrastructural Characterization of PEGylation-associated Vacuolation in Nonclinical Models.

Forest T, Xu Q, Kuruvilla S, Vu H, Vlasakova K, Glaab WE, Hines C, Xun S. Forest T, et al. Among authors: xu q. Toxicol Pathol. 2017 Jul;45(5):604-613. doi: 10.1177/0192623317714068. Epub 2017 Jul 4. Toxicol Pathol. 2017. PMID: 28673196

6

Metabolic profiles show specific mitochondrial toxicities in vitro in myotube cells.

Xu Q, Vu H, Liu L, Wang TC, Schaefer WH. Xu Q, et al. J Biomol NMR. 2011 Apr;49(3-4):207-19. doi: 10.1007/s10858-011-9482-8. Epub 2011 Feb 26. J Biomol NMR. 2011. PMID: 21359514

7

Metabolomics in pharmaceutical research and development: metabolites, mechanisms and pathways.

Xu EY, Schaefer WH, Xu Q. Xu EY, et al. Among authors: xu q. Curr Opin Drug Discov Devel. 2009 Jan;12(1):40-52. Curr Opin Drug Discov Devel. 2009. PMID: 19152212 Review.

8

Characterization and quantification of C-polysaccharide in Streptococcus pneumoniae capsular polysaccharide preparations.

Xu Q, Abeygunawardana C, Ng AS, Sturgess AW, Harmon BJ, Hennessey JP Jr. Xu Q, et al. Anal Biochem. 2005 Jan 15;336(2):262-72. doi: 10.1016/j.ab.2004.10.019. Anal Biochem. 2005. PMID: 15620891

9

Quantitative nuclear magnetic resonance analysis and characterization of the derivatized Haemophilus influenzae type b polysaccharide intermediate for PedvaxHIB.

Xu Q, Klees J, Teyral J, Capen R, Huang M, Sturgess AW, Hennessey JP Jr, Washabaugh M, Sitrin R, Abeygunawardana C. Xu Q, et al. Anal Biochem. 2005 Feb 15;337(2):235-45. doi: 10.1016/j.ab.2004.11.019. Anal Biochem. 2005. PMID: 15691503

10

Quantification and identification of components in solution mixtures from 1D proton NMR spectra using singular value decomposition.

Xu Q, Sachs JR, Wang TC, Schaefer WH. Xu Q, et al. Anal Chem. 2006 Oct 15;78(20):7175-85. doi: 10.1021/ac0606857. Anal Chem. 2006. PMID: 17037918

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