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Page 1
USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer.
Reissland M, Hartmann O, Tauch S, Bugter JM, Prieto-Garcia C, Schulte C, Loebbert S, Solvie D, Bitman-Lotan E, Narain A, Jacomin AC, Schuelein-Voelk C, Fuss CT, Pahor N, Ade C, Buck V, Potente M, Li V, Beliu G, Wiegering A, Grossmann T, Eilers M, Wolf E, Maric H, Rosenfeldt M, Maurice MM, Dikic I, Gallant P, Orian A, Diefenbacher ME. Reissland M, et al. Among authors: solvie d. Oncogene. 2024 Dec;43(50):3645-3659. doi: 10.1038/s41388-024-03141-x. Epub 2024 Oct 23. Oncogene. 2024. PMID: 39443725 Free PMC article.
NEAT1 promotes genome stability via m6A methylation-dependent regulation of CHD4.
Mamontova V, Trifault B, Gribling-Burrer AS, Bohn P, Boten L, Preckwinkel P, Gallant P, Solvie D, Ade CP, Papadopoulos D, Eilers M, Gutschner T, Smyth RP, Burger K. Mamontova V, et al. Among authors: solvie d. Genes Dev. 2024 Oct 16;38(17-20):915-930. doi: 10.1101/gad.351913.124. Genes Dev. 2024. PMID: 39362776 Free PMC article.
Nucleolar detention of NONO shields DNA double-strand breaks from aberrant transcripts.
Trifault B, Mamontova V, Cossa G, Ganskih S, Wei Y, Hofstetter J, Bhandare P, Baluapuri A, Nieto B, Solvie D, Ade CP, Gallant P, Wolf E, Larsen DH, Munschauer M, Burger K. Trifault B, et al. Among authors: solvie d. Nucleic Acids Res. 2024 Apr 12;52(6):3050-3068. doi: 10.1093/nar/gkae022. Nucleic Acids Res. 2024. PMID: 38224452 Free PMC article.
MYC multimers shield stalled replication forks from RNA polymerase.
Solvie D, Baluapuri A, Uhl L, Fleischhauer D, Endres T, Papadopoulos D, Aziba A, Gaballa A, Mikicic I, Isaakova E, Giansanti C, Jansen J, Jungblut M, Klein T, Schülein-Völk C, Maric H, Doose S, Sauer M, Beli P, Rosenwald A, Dobbelstein M, Wolf E, Eilers M. Solvie D, et al. Nature. 2022 Dec;612(7938):148-155. doi: 10.1038/s41586-022-05469-4. Epub 2022 Nov 23. Nature. 2022. PMID: 36424410
MYCN recruits the nuclear exosome complex to RNA polymerase II to prevent transcription-replication conflicts.
Papadopoulos D, Solvie D, Baluapuri A, Endres T, Ha SA, Herold S, Kalb J, Giansanti C, Schülein-Völk C, Ade CP, Schneider C, Gaballa A, Vos S, Fischer U, Dobbelstein M, Wolf E, Eilers M. Papadopoulos D, et al. Among authors: solvie d. Mol Cell. 2022 Jan 6;82(1):159-176.e12. doi: 10.1016/j.molcel.2021.11.002. Epub 2021 Nov 29. Mol Cell. 2022. PMID: 34847357 Free article.
Ubiquitylation of MYC couples transcription elongation with double-strand break repair at active promoters.
Endres T, Solvie D, Heidelberger JB, Andrioletti V, Baluapuri A, Ade CP, Muhar M, Eilers U, Vos SM, Cramer P, Zuber J, Beli P, Popov N, Wolf E, Gallant P, Eilers M. Endres T, et al. Among authors: solvie d. Mol Cell. 2021 Feb 18;81(4):830-844.e13. doi: 10.1016/j.molcel.2020.12.035. Epub 2021 Jan 15. Mol Cell. 2021. PMID: 33453168 Free PMC article.
Recruitment of BRCA1 limits MYCN-driven accumulation of stalled RNA polymerase.
Herold S, Kalb J, Büchel G, Ade CP, Baluapuri A, Xu J, Koster J, Solvie D, Carstensen A, Klotz C, Rodewald S, Schülein-Völk C, Dobbelstein M, Wolf E, Molenaar J, Versteeg R, Walz S, Eilers M. Herold S, et al. Among authors: solvie d. Nature. 2019 Mar;567(7749):545-549. doi: 10.1038/s41586-019-1030-9. Epub 2019 Mar 20. Nature. 2019. PMID: 30894746 Free PMC article.