Casan J - Search Results

1

Principles of CRISPR-Cas13 mismatch intolerance enable selective silencing of point-mutated oncogenic RNA with single-base precision.

Shembrey C, Yang R, Casan J, Hu W, Chen H, Singh GJ, Sadras T, Prasad K, Shortt J, Johnstone RW, Trapani JA, Ekert PG, Fareh M. Shembrey C, et al. Among authors: casan j. Sci Adv. 2024 Dec 20;10(51):eadl0731. doi: 10.1126/sciadv.adl0731. Epub 2024 Dec 18. Sci Adv. 2024. PMID: 39693429 Free PMC article.

2

Tranexamic acid versus placebo to prevent bleeding in patients with haematological malignancies and severe thrombocytopenia (TREATT): a randomised, double-blind, parallel, phase 3 superiority trial.

TREATT Trial Investigators. TREATT Trial Investigators. Lancet Haematol. 2024 Dec 3:S2352-3026(24)00317-X. doi: 10.1016/S2352-3026(24)00317-X. Online ahead of print. Lancet Haematol. 2024. PMID: 39642900

3

Single-base tiled screen unveils design principles of PspCas13b for potent and off-target-free RNA silencing.

Hu W, Kumar A, Ahmed SF, Qi S, Ma DKG, Chen H, Singh GJ, Casan JML, Haber M, Voskoboinik I, McKay MR, Trapani JA, Ekert PG, Fareh M. Hu W, et al. Among authors: casan jml. Nat Struct Mol Biol. 2024 Nov;31(11):1702-1716. doi: 10.1038/s41594-024-01336-0. Epub 2024 Jul 1. Nat Struct Mol Biol. 2024. PMID: 38951623 Free PMC article.

4

Venetoclax-rituximab is active in patients with BTKi-exposed CLL, but durable treatment-free remissions are uncommon.

Lew TE, Bennett R, Lin VS, Whitechurch A, Handunnetti SM, Marlton P, Shen Y, Mulligan SP, Casan J, Blombery P, Tam CS, Roberts AW, Seymour JF, Thompson PA, Anderson MA. Lew TE, et al. Among authors: casan j. Blood Adv. 2024 Mar 26;8(6):1439-1443. doi: 10.1182/bloodadvances.2023011327. Blood Adv. 2024. PMID: 38231032 Free PMC article. No abstract available.

5

Degraders upgraded: the rise of PROTACs in hematological malignancies.

Casan JML, Seymour JF. Casan JML, et al. Blood. 2024 Mar 28;143(13):1218-1230. doi: 10.1182/blood.2023022993. Blood. 2024. PMID: 38170175 Review.

6

Kaempferol-3-rhamnoside overaccumulation in flavonoid 3'-hydroxylase tt7 mutants compromises seed coat outer integument differentiation and seed longevity.

Niñoles R, Arjona P, Azad SM, Hashim A, Casañ J, Bueso E, Serrano R, Espinosa A, Molina I, Gadea J. Niñoles R, et al. Among authors: casan j. New Phytol. 2023 May;238(4):1461-1478. doi: 10.1111/nph.18836. Epub 2023 Mar 12. New Phytol. 2023. PMID: 36829299 Free article.

7

Improving outcomes for patients with lymphoma: design and development of the Australian and New Zealand Lymphoma and Related Diseases Registry.

Lymphoma and Related Diseases Registry Investigators. Lymphoma and Related Diseases Registry Investigators. BMC Med Res Methodol. 2022 Oct 10;22(1):266. doi: 10.1186/s12874-022-01728-0. BMC Med Res Methodol. 2022. PMID: 36217114 Free PMC article.

8

Transcription Factor DOF4.1 Regulates Seed Longevity in Arabidopsis via Seed Permeability and Modulation of Seed Storage Protein Accumulation.

Niñoles R, Ruiz-Pastor CM, Arjona-Mudarra P, Casañ J, Renard J, Bueso E, Mateos R, Serrano R, Gadea J. Niñoles R, et al. Among authors: casan j. Front Plant Sci. 2022 Jul 1;13:915184. doi: 10.3389/fpls.2022.915184. eCollection 2022. Front Plant Sci. 2022. PMID: 35845633 Free PMC article.

9

Reprogrammed CRISPR-Cas13b suppresses SARS-CoV-2 replication and circumvents its mutational escape through mismatch tolerance.

Fareh M, Zhao W, Hu W, Casan JML, Kumar A, Symons J, Zerbato JM, Fong D, Voskoboinik I, Ekert PG, Rudraraju R, Purcell DFJ, Lewin SR, Trapani JA. Fareh M, et al. Among authors: casan jml. Nat Commun. 2021 Jul 13;12(1):4270. doi: 10.1038/s41467-021-24577-9. Nat Commun. 2021. PMID: 34257311 Free PMC article.

10

Cytarabine-based induction immunochemotherapy in the front-line treatment of older patients with mantle cell lymphoma.

Ratnasingam S, Casan J, Shortt J, Hawkes E, Gilbertson M, McQuilten Z, Grigoriadis G, Htun KT, Htet SM, Campbell P, Chai KL, Quach H, Patil S, Opat S. Ratnasingam S, et al. Among authors: casan j. Sci Rep. 2019 Sep 19;9(1):13544. doi: 10.1038/s41598-019-49776-9. Sci Rep. 2019. PMID: 31537857 Free PMC article.

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