Nolan EM - Search Results

1

Spectroscopic and computational investigations of Cobalt(II) binding to the innate immune protein human calprotectin.

Killian MM, Brophy MB, Nolan EM, Brunold TC. Killian MM, et al. Among authors: nolan em. J Biol Inorg Chem. 2024 Feb;29(1):127-137. doi: 10.1007/s00775-023-02034-w. Epub 2024 Jan 17. J Biol Inorg Chem. 2024. PMID: 38233645

2

Calcium ion gradients modulate the zinc affinity and antibacterial activity of human calprotectin.

Brophy MB, Hayden JA, Nolan EM. Brophy MB, et al. Among authors: nolan em. J Am Chem Soc. 2012 Oct 31;134(43):18089-100. doi: 10.1021/ja307974e. Epub 2012 Oct 19. J Am Chem Soc. 2012. PMID: 23082970 Free PMC article.

3

High-affinity manganese coordination by human calprotectin is calcium-dependent and requires the histidine-rich site formed at the dimer interface.

Hayden JA, Brophy MB, Cunden LS, Nolan EM. Hayden JA, et al. Among authors: nolan em. J Am Chem Soc. 2013 Jan 16;135(2):775-87. doi: 10.1021/ja3096416. Epub 2012 Dec 31. J Am Chem Soc. 2013. PMID: 23276281 Free PMC article.

4

Contributions of the S100A9 C-terminal tail to high-affinity Mn(II) chelation by the host-defense protein human calprotectin.

Brophy MB, Nakashige TG, Gaillard A, Nolan EM. Brophy MB, et al. Among authors: nolan em. J Am Chem Soc. 2013 Nov 27;135(47):17804-17. doi: 10.1021/ja407147d. Epub 2013 Nov 18. J Am Chem Soc. 2013. PMID: 24245608 Free PMC article.

5

Impaired cholecystokinin-induced gallbladder emptying incriminated in spontaneous "black" pigment gallstone formation in germfree Swiss Webster mice.

Woods SE, Leonard MR, Hayden JA, Brophy MB, Bernert KR, Lavoie B, Muthupalani S, Whary MT, Mawe GM, Nolan EM, Carey MC, Fox JG. Woods SE, et al. Among authors: nolan em. Am J Physiol Gastrointest Liver Physiol. 2015 Feb 15;308(4):G335-49. doi: 10.1152/ajpgi.00314.2014. Epub 2014 Dec 4. Am J Physiol Gastrointest Liver Physiol. 2015. PMID: 25477375 Free PMC article.

6

Manganese and microbial pathogenesis: sequestration by the Mammalian immune system and utilization by microorganisms.

Brophy MB, Nolan EM. Brophy MB, et al. Among authors: nolan em. ACS Chem Biol. 2015 Mar 20;10(3):641-51. doi: 10.1021/cb500792b. Epub 2015 Jan 16. ACS Chem Biol. 2015. PMID: 25594606 Free PMC article. Review.

7

Manganese binding properties of human calprotectin under conditions of high and low calcium: X-ray crystallographic and advanced electron paramagnetic resonance spectroscopic analysis.

Gagnon DM, Brophy MB, Bowman SE, Stich TA, Drennan CL, Britt RD, Nolan EM. Gagnon DM, et al. Among authors: nolan em. J Am Chem Soc. 2015 Mar 4;137(8):3004-16. doi: 10.1021/ja512204s. Epub 2015 Feb 18. J Am Chem Soc. 2015. PMID: 25597447 Free PMC article.

8

The Hexahistidine Motif of Host-Defense Protein Human Calprotectin Contributes to Zinc Withholding and Its Functional Versatility.

Nakashige TG, Stephan JR, Cunden LS, Brophy MB, Wommack AJ, Keegan BC, Shearer JM, Nolan EM. Nakashige TG, et al. Among authors: nolan em. J Am Chem Soc. 2016 Sep 21;138(37):12243-51. doi: 10.1021/jacs.6b06845. Epub 2016 Sep 7. J Am Chem Soc. 2016. PMID: 27541598 Free PMC article.

9

Biochemical and Functional Evaluation of the Intramolecular Disulfide Bonds in the Zinc-Chelating Antimicrobial Protein Human S100A7 (Psoriasin).

Cunden LS, Brophy MB, Rodriguez GE, Flaxman HA, Nolan EM. Cunden LS, et al. Among authors: nolan em. Biochemistry. 2017 Oct 31;56(43):5726-5738. doi: 10.1021/acs.biochem.7b00781. Epub 2017 Oct 19. Biochemistry. 2017. PMID: 28976190 Free PMC article.

10

Biochemical and Spectroscopic Observation of Mn(II) Sequestration from Bacterial Mn(II) Transport Machinery by Calprotectin.

Hadley RC, Gagnon DM, Brophy MB, Gu Y, Nakashige TG, Britt RD, Nolan EM. Hadley RC, et al. Among authors: nolan em. J Am Chem Soc. 2018 Jan 10;140(1):110-113. doi: 10.1021/jacs.7b11207. Epub 2017 Dec 20. J Am Chem Soc. 2018. PMID: 29211955 Free PMC article.

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