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Page 1
Mesothelin expression correlates with elevated inhibitory immune activity in patients with colorectal cancer.
Malla M, Kumar Deshkmukh S, Wu S, Samec T, Olevian D, Naili R, Bassel ER, Xiu J, Farrell A, Lenz HJ, Lou E, Goel S, Spetzler D, Goldberg RM, Hazlehurst L. Malla M, et al. Among authors: spetzler d. Res Sq [Preprint]. 2023 Dec 28:rs.3.rs-3787873. doi: 10.21203/rs.3.rs-3787873/v1. Res Sq. 2023. Update in: Cancer Gene Ther. 2024 Oct;31(10):1547-1558. doi: 10.1038/s41417-024-00816-1 PMID: 38234761 Free PMC article. Updated. Preprint.
Multi-omic characterization reveals a distinct molecular landscape in young-onset pancreatic cancer.
Ogobuiro I, Baca Y, Ribeiro JR, Walker P, Wilson GC, Gulhati P, Marshall JL, Shroff RT, Spetzler D, Oberley MJ, Abbott DE, Kim HJ, Kooby DA, Maithel SK, Ahmad SA, Merchant NB, Xiu J, Hosein PJ, Datta J. Ogobuiro I, et al. Among authors: spetzler d. medRxiv [Preprint]. 2023 Mar 29:2023.03.28.23287894. doi: 10.1101/2023.03.28.23287894. medRxiv. 2023. Update in: JCO Precis Oncol. 2023 Sep;7:e2300152. doi: 10.1200/PO.23.00152 PMID: 37034762 Free PMC article. Updated. Preprint.
Mutation burden and anti-PD-1 outcomes are not universally associated with immune cell infiltration or lymphoid activation.
Hsiehchen D, Elliott A, Xiu J, Seeber A, El-Deiry W, Antonarakis ES, Graff SL, Hall MJ, Borghaei H, Hoon DSB, Liu SV, Ma PC, McKay RR, Wise-Draper T, Marshall J, Sledge GW, Spetzler D, Zhu H. Hsiehchen D, et al. Among authors: spetzler d. Cancer Cell. 2024 Dec 9;42(12):1985-1987. doi: 10.1016/j.ccell.2024.10.017. Epub 2024 Nov 21. Cancer Cell. 2024. PMID: 39577419
Analysis of Concordance Between Next-Generation Sequencing Assessment of Microsatellite Instability and Immunohistochemistry-Mismatch Repair From Solid Tumors.
Ali-Fehmi R, Krause HB, Morris RT, Wallbillich JJ, Corey L, Bandyopadhyay S, Kheil M, Elbashir L, Zaiem F, Quddus MR, Abada E, Herzog T, Karnezis AN, Antonarakis ES, Kasi PM, Wei S, Swensen J, Elliott A, Xiu J, Hechtman J, Spetzler D, Abraham J, Radovich M, Sledge G, Oberley MJ, Bryant D. Ali-Fehmi R, et al. Among authors: spetzler d. JCO Precis Oncol. 2024 Oct;8:e2300648. doi: 10.1200/PO.23.00648. Epub 2024 Nov 20. JCO Precis Oncol. 2024. PMID: 39565978 Free PMC article.
Use of Oncogene Overlap by Tissue-Based Next-Generation Sequencing to Explore the Mutational Landscape and Survival Impact of HER2, KRAS and MET Copy-Number Gain in Nonsmall Cell Lung Cancer.
Watson AS, Krause HB, Elliott A, Farrell A, Liu SV, Ma PC, VanderWalde A, Sledge GW, Spetzler D, Schenk EL, Camidge DR. Watson AS, et al. Among authors: spetzler d. Clin Lung Cancer. 2024 Dec;25(8):712-722.e1. doi: 10.1016/j.cllc.2024.09.001. Epub 2024 Sep 12. Clin Lung Cancer. 2024. PMID: 39384504
Selective loss of Y chromosomes in lung adenocarcinoma modulates the tumor immune environment through cancer/testis antigens.
Fischer J, Shutta KH, Chen C, Fanfani V, Saha E, Mandros P, Ben Guebila M, Xiu J, Nieva J, Liu S, Uprety D, Spetzler D, Lopes-Ramos CM, DeMeo D, Quackenbush J. Fischer J, et al. Among authors: spetzler d. bioRxiv [Preprint]. 2024 Sep 22:2024.09.19.613876. doi: 10.1101/2024.09.19.613876. bioRxiv. 2024. PMID: 39345481 Free PMC article. Preprint.
Clinical and Genomic Features of Classical and Basal Transcriptional Subtypes in Pancreatic Cancer.
Singh H, Xiu J, Kapner KS, Yuan C, Narayan RR, Oberley M, Farrell A, Surana R, Huffman BM, Perez K, Cleary JM, Jordan AC, Dias Costa A, Williams HL, Raghavan S, Weinberg B, Pishvaian MJ, Shroff RT, Goel S, Dougan SK, Nowak JA, Spetzler D, Sledge G, Wolpin BM, Aguirre AJ. Singh H, et al. Among authors: spetzler d. Clin Cancer Res. 2024 Nov 1;30(21):4932-4942. doi: 10.1158/1078-0432.CCR-24-1164. Clin Cancer Res. 2024. PMID: 39283131
Consensus molecular subtyping of metastatic colorectal cancer expands biomarker-directed therapeutic benefit for patients with CMS1 and CMS2 tumors.
Chowdhury S, Xiu J, Ribeiro JR, Nicolaides T, Zhang J, Korn WM, Poorman KA, Lenz HJ, Marshall JL, Oberley MJ, Sledge GW Jr, Spetzler D, Kopetz S, Shen JP. Chowdhury S, et al. Among authors: spetzler d. Br J Cancer. 2024 Nov;131(8):1328-1339. doi: 10.1038/s41416-024-02826-0. Epub 2024 Sep 4. Br J Cancer. 2024. PMID: 39227409
Mesothelin expression correlates with elevated inhibitory immune activity in patients with colorectal cancer.
Malla M, Deshmukh SK, Wu S, Samec T, Olevian DC, El Naili R, El-Rayes B, Xiu J, Farrell A, Lenz HJ, Lou E, Goel S, Spetzler D, Goldberg RM, Hazlehurst L. Malla M, et al. Among authors: spetzler d. Cancer Gene Ther. 2024 Oct;31(10):1547-1558. doi: 10.1038/s41417-024-00816-1. Epub 2024 Aug 22. Cancer Gene Ther. 2024. PMID: 39174744 Free PMC article.
70 results