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SARS-CoV-2 infection causes dopaminergic neuron senescence.
Yang L, Kim TW, Han Y, Nair MS, Harschnitz O, Zhu J, Wang P, Koo SY, Lacko LA, Chandar V, Bram Y, Zhang T, Zhang W, He F, Pan C, Wu J, Huang Y, Evans T, van der Valk P, Titulaer MJ, Spoor JKH, Furler O'Brien RL, Bugiani M, D J Van de Berg W, Schwartz RE, Ho DD, Studer L, Chen S. Yang L, et al. Cell Stem Cell. 2024 Feb 1;31(2):196-211.e6. doi: 10.1016/j.stem.2023.12.012. Epub 2024 Jan 17. Cell Stem Cell. 2024. PMID: 38237586 Free PMC article.
Identification of Candidate COVID-19 Therapeutics using hPSC-derived Lung Organoids.
Han Y, Yang L, Duan X, Duan F, Nilsson-Payant BE, Yaron TM, Wang P, Tang X, Zhang T, Zhao Z, Bram Y, Redmond D, Houghton S, Nguyen D, Xu D, Wang X, Uhl S, Huang Y, Johnson JL, Xiang J, Wang H, Pan FC, Cantley LC, tenOever BR, Ho DD, Evans T, Schwartz RE, Chen HJ, Chen S. Han Y, et al. Among authors: yang l. bioRxiv [Preprint]. 2020 May 5:2020.05.05.079095. doi: 10.1101/2020.05.05.079095. bioRxiv. 2020. PMID: 32511403 Free PMC article. Preprint.
A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids.
Yang L, Han Y, Nilsson-Payant BE, Gupta V, Wang P, Duan X, Tang X, Zhu J, Zhao Z, Jaffré F, Zhang T, Kim TW, Harschnitz O, Redmond D, Houghton S, Liu C, Naji A, Ciceri G, Guttikonda S, Bram Y, Nguyen DT, Cioffi M, Chandar V, Hoagland DA, Huang Y, Xiang J, Wang H, Lyden D, Borczuk A, Chen HJ, Studer L, Pan FC, Ho DD, tenOever BR, Evans T, Schwartz RE, Chen S. Yang L, et al. Cell Stem Cell. 2020 Jul 2;27(1):125-136.e7. doi: 10.1016/j.stem.2020.06.015. Epub 2020 Jun 19. Cell Stem Cell. 2020. PMID: 32579880 Free PMC article.
Modeling COVID-19 with Human Pluripotent Stem Cell-Derived Cells Reveals Synergistic Effects of Anti-inflammatory Macrophages with ACE2 Inhibition Against SARS-CoV-2.
Duan F, Guo L, Yang L, Han Y, Thakur A, Nilsson-Payant BE, Wang P, Zhang Z, Yan Ma C, Zhou X, Han T, Zhang T, Wang X, Xu D, Duan X, Xiang J, Tse HF, Liao C, Luo W, Huang FP, Chen YW, Evans T, Schwartz RE, tenOever B, Ho DD, Chen S, Na J, Lian Q, Chen HJ. Duan F, et al. Among authors: yang l. Res Sq [Preprint]. 2020 Sep 15:rs.3.rs-62758. doi: 10.21203/rs.3.rs-62758/v1. Res Sq. 2020. PMID: 32839764 Free PMC article. Preprint.
Identification of SARS-CoV-2 inhibitors using lung and colonic organoids.
Han Y, Duan X, Yang L, Nilsson-Payant BE, Wang P, Duan F, Tang X, Yaron TM, Zhang T, Uhl S, Bram Y, Richardson C, Zhu J, Zhao Z, Redmond D, Houghton S, Nguyen DT, Xu D, Wang X, Jessurun J, Borczuk A, Huang Y, Johnson JL, Liu Y, Xiang J, Wang H, Cantley LC, tenOever BR, Ho DD, Pan FC, Evans T, Chen HJ, Schwartz RE, Chen S. Han Y, et al. Among authors: yang l. Nature. 2021 Jan;589(7841):270-275. doi: 10.1038/s41586-020-2901-9. Epub 2020 Oct 28. Nature. 2021. PMID: 33116299 Free PMC article.
SARS-CoV-2 Infected Cardiomyocytes Recruit Monocytes by Secreting CCL2.
Chen S, Yang L, Nilsson-Payant B, Han Y, Jaffré F, Zhu J, Wang P, Zhang T, Redmond D, Houghton S, Møller R, Hoagland D, Horiuchi S, Acklin J, Lim J, Bram Y, Richardson C, Chandar V, Borczuk A, Huang Y, Xiang J, Ho D, Schwartz R, tenOever B, Evans T. Chen S, et al. Among authors: yang l. Res Sq [Preprint]. 2020 Nov 17:rs.3.rs-94634. doi: 10.21203/rs.3.rs-94634/v1. Res Sq. 2020. Update in: Stem Cell Reports. 2021 Sep 14;16(9):2274-2288. doi: 10.1016/j.stemcr.2021.07.012 PMID: 33236003 Free PMC article. Updated. Preprint.
An Immuno-Cardiac Model for Macrophage-Mediated Inflammation in COVID-19 Hearts.
Yang L, Han Y, Jaffré F, Nilsson-Payant BE, Bram Y, Wang P, Zhu J, Zhang T, Redmond D, Houghton S, Uhl S, Borczuk A, Huang Y, Richardson C, Chandar V, Acklin JA, Lim JK, Chen Z, Xiang J, Ho DD, tenOever BR, Schwartz RE, Evans T, Chen S. Yang L, et al. Circ Res. 2021 Jun 25;129(1):33-46. doi: 10.1161/CIRCRESAHA.121.319060. Epub 2021 Apr 15. Circ Res. 2021. PMID: 33853355 Free PMC article.
SARS-CoV-2 Infection Causes Dopaminergic Neuron Senescence.
Han Y, Yang L, Kim TW, Nair MS, Harschnitz O, Wang P, Zhu J, Koo SY, Tang X, Lacko LA, Chandar V, Bram Y, Zhang T, Zhang W, He F, Caicedo J, Huang Y, Evans T, van der Valk P, Titulaer MJ, Spoor JKH, Furler RL, Canoll P, Goldman JE, Przedborski S, Schwartz RE, Ho DD, Studer L, Chen S. Han Y, et al. Among authors: yang l. Res Sq [Preprint]. 2021 May 21:rs.3.rs-513461. doi: 10.21203/rs.3.rs-513461/v1. Res Sq. 2021. Update in: Cell Stem Cell. 2024 Feb 1;31(2):196-211.e6. doi: 10.1016/j.stem.2023.12.012 PMID: 34031650 Free PMC article. Updated. Preprint.
Cardiomyocytes recruit monocytes upon SARS-CoV-2 infection by secreting CCL2.
Yang L, Nilsson-Payant BE, Han Y, Jaffré F, Zhu J, Wang P, Zhang T, Redmond D, Houghton S, Møller R, Hoagland D, Carrau L, Horiuchi S, Goff M, Lim JK, Bram Y, Richardson C, Chandar V, Borczuk A, Huang Y, Xiang J, Ho DD, Schwartz RE, tenOever BR, Evans T, Chen S. Yang L, et al. Stem Cell Reports. 2021 Sep 14;16(9):2274-2288. doi: 10.1016/j.stemcr.2021.07.012. Epub 2021 Jul 20. Stem Cell Reports. 2021. PMID: 34403650 Free PMC article.
Cardiomyocytes recruit monocytes upon SARS-CoV-2 infection by secreting CCL2.
Yang L, Nilsson-Payant BE, Han Y, Jaffré F, Zhu J, Wang P, Zhang T, Redmond D, Houghton S, Møller R, Hoagland D, Carrau L, Horiuchi S, Goff M, Lim JK, Bram Y, Richardson C, Chandar V, Borczuk A, Huang Y, Xiang J, Ho DD, Schwartz RE, tenOever BR, Evans T, Chen S. Yang L, et al. Stem Cell Reports. 2021 Oct 12;16(10):2565. doi: 10.1016/j.stemcr.2021.09.008. Stem Cell Reports. 2021. PMID: 34644531 Free PMC article. No abstract available.
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