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Physiologists as medical scientists: An early warning from the German academic system.
Streckfuss-Bömeke K, Kränkel N, Maack C, Schnabel RB, Zelarayán LC, Frey N, Jezzard P, Krüger M, Lachmann N, Lutz S, Noack C, Schoger E, Schröder K, Sommerfeld LC, Steffens S, Winkels H, Würtz C, Zeller T, Rog-Zielinska EA, Kohl P. Streckfuss-Bömeke K, et al. Among authors: sommerfeld lc. Physiol Rep. 2024 Nov;12(21):e70055. doi: 10.14814/phy2.70055. Physiol Rep. 2024. PMID: 39462686 Free PMC article. Review.
Biomarker-based prediction of sinus rhythm in atrial fibrillation patients: the EAST-AFNET 4 biomolecule study.
Fabritz L, Al-Taie C, Borof K, Breithardt G, Camm AJ, Crijns HJGM, Roth Cardoso V, Chua W, van Elferen S, Eckardt L, Gkoutos G, Goette A, Guasch E, Hatem S, Metzner A, Mont L, Murukutla VA, Obergassel J, Rillig A, Sinner MF, Schnabel RB, Schotten U, Sommerfeld LC, Wienhues-Thelen UH, Zapf A, Zeller T, Kirchhof P. Fabritz L, et al. Among authors: sommerfeld lc. Eur Heart J. 2024 Dec 16;45(47):5002-5019. doi: 10.1093/eurheartj/ehae611. Eur Heart J. 2024. PMID: 39215973 Free PMC article.
PITX2 deficiency leads to atrial mitochondrial dysfunction.
Reyat JS, Sommerfeld LC, O'Reilly M, Roth Cardoso V, Thiemann E, Khan AO, O'Shea C, Harder S, Müller C, Barlow J, Stapley RJ, Chua W, Kabir SN, Grech O, Hummel O, Hübner N, Kääb S, Mont L, Hatem SN, Winters J, Zeemering S, Morgan NV, Rayes J, Gehmlich K, Stoll M, Brand T, Schweizer M, Piasecki A, Schotten U, Gkoutos GV, Lorenz K, Cuello F, Kirchhof P, Fabritz L. Reyat JS, et al. Among authors: sommerfeld lc. Cardiovasc Res. 2024 Dec 4;120(15):1907-1923. doi: 10.1093/cvr/cvae169. Cardiovasc Res. 2024. PMID: 39129206 Free PMC article.
Reduced plakoglobin increases the risk of sodium current defects and atrial conduction abnormalities in response to androgenic anabolic steroid abuse.
Sommerfeld LC, Holmes AP, Yu TY, O'Shea C, Kavanagh DM, Pike JM, Wright T, Syeda F, Aljehani A, Kew T, Cardoso VR, Kabir SN, Hepburn C, Menon PR, Broadway-Stringer S, O'Reilly M, Witten A, Fortmueller L, Lutz S, Kulle A, Gkoutos GV, Pavlovic D, Arlt W, Lavery GG, Steeds R, Gehmlich K, Stoll M, Kirchhof P, Fabritz L. Sommerfeld LC, et al. J Physiol. 2024 Sep;602(18):4409-4436. doi: 10.1113/JP284597. Epub 2024 Feb 12. J Physiol. 2024. PMID: 38345865
An angiopoietin 2, FGF23, and BMP10 biomarker signature differentiates atrial fibrillation from other concomitant cardiovascular conditions.
Chua W, Cardoso VR, Guasch E, Sinner MF, Al-Taie C, Brady P, Casadei B, Crijns HJGM, Dudink EAMP, Hatem SN, Kääb S, Kastner P, Mont L, Nehaj F, Purmah Y, Reyat JS, Schotten U, Sommerfeld LC, Zeemering S, Ziegler A, Gkoutos GV, Kirchhof P, Fabritz L. Chua W, et al. Among authors: sommerfeld lc. Sci Rep. 2023 Oct 5;13(1):16743. doi: 10.1038/s41598-023-42331-7. Sci Rep. 2023. PMID: 37798357 Free PMC article.
Familial atrial fibrillation mutation M1875T-SCN5A increases early sodium current and dampens the effect of flecainide.
O'Reilly M, Sommerfeld LC, O'Shea C, Broadway-Stringer S, Andaleeb S, Reyat JS, Kabir SN, Stastny D, Malinova A, Delbue D, Fortmueller L, Gehmlich K, Pavlovic D, Skryabin BV, Holmes AP, Kirchhof P, Fabritz L. O'Reilly M, et al. Among authors: sommerfeld lc. Europace. 2023 Mar 30;25(3):1152-1161. doi: 10.1093/europace/euac218. Europace. 2023. PMID: 36504385 Free PMC article.
High resolution optical mapping of cardiac electrophysiology in pre-clinical models.
O'Shea C, Winter J, Kabir SN, O'Reilly M, Wells SP, Baines O, Sommerfeld LC, Correia J, Lei M, Kirchhof P, Holmes AP, Fabritz L, Rajpoot K, Pavlovic D. O'Shea C, et al. Among authors: sommerfeld lc. Sci Data. 2022 Mar 31;9(1):135. doi: 10.1038/s41597-022-01253-1. Sci Data. 2022. PMID: 35361792 Free PMC article.
13 results