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Zoonosis and zooanthroponosis of emerging respiratory viruses.
Khalil AM, Martinez-Sobrido L, Mostafa A. Khalil AM, et al. Front Cell Infect Microbiol. 2024 Jan 5;13:1232772. doi: 10.3389/fcimb.2023.1232772. eCollection 2023. Front Cell Infect Microbiol. 2024. PMID: 38249300 Free PMC article. Review.
Identification of a conserved S2 epitope present on spike proteins from all highly pathogenic coronaviruses.
Silva RP, Huang Y, Nguyen AW, Hsieh CL, Olaluwoye OS, Kaoud TS, Wilen RE, Qerqez AN, Park JG, Khalil AM, Azouz LR, Le KC, Bohanon AL, DiVenere AM, Liu Y, Lee AG, Amengor DA, Shoemaker SR, Costello SM, Padlan EA, Marqusee S, Martinez-Sobrido L, Dalby KN, D'Arcy S, McLellan JS, Maynard JA. Silva RP, et al. Elife. 2023 Mar 21;12:e83710. doi: 10.7554/eLife.83710. Elife. 2023. PMID: 36942851 Free PMC article.
Anticancer pan-ErbB inhibitors reduce inflammation and tissue injury and exert broad-spectrum antiviral effects.
Saul S, Karim M, Ghita L, Huang PT, Chiu W, Durán V, Lo CW, Kumar S, Bhalla N, Leyssen P, Alem F, Boghdeh NA, Tran DH, Cohen CA, Brown JA, Huie KE, Tindle C, Sibai M, Ye C, Khalil AM, Chiem K, Martinez-Sobrido L, Dye JM, Pinsky BA, Ghosh P, Das S, Solow-Cordero DE, Jin J, Wikswo JP, Jochmans D, Neyts J, De Jonghe S, Narayanan A, Einav S. Saul S, et al. J Clin Invest. 2023 Oct 2;133(19):e169510. doi: 10.1172/JCI169510. J Clin Invest. 2023. PMID: 37581931 Free PMC article.
Anti-rheumatic colchicine phytochemical exhibits potent antiviral activities against avian and seasonal Influenza A viruses (IAVs) via targeting different stages of IAV replication cycle.
Hegazy A, Soltane R, Alasiri A, Mostafa I, Metwaly AM, Eissa IH, Mahmoud SH, Allayeh AK, Shama NMA, Khalil AA, Barre RS, El-Shazly AM, Ali MA, Martinez-Sobrido L, Mostafa A. Hegazy A, et al. BMC Complement Med Ther. 2024 Jan 22;24(1):49. doi: 10.1186/s12906-023-04303-2. BMC Complement Med Ther. 2024. PMID: 38254071 Free PMC article.
Influenza A virus replicates productively in primary human kidney cells and induces factors and mechanisms related to regulated cell death and renal pathology observed in virus-infected patients.
Koch B, Shehata M, Müller-Ruttloff C, Gouda SA, Wetzstein N, Patyna S, Scholz A, Schmid T, Dietrich U, Münch C, Ziebuhr J, Geiger H, Martinez-Sobrido L, Baer PC, Mostafa A, Pleschka S. Koch B, et al. Front Cell Infect Microbiol. 2024 Mar 25;14:1363407. doi: 10.3389/fcimb.2024.1363407. eCollection 2024. Front Cell Infect Microbiol. 2024. PMID: 38590437 Free PMC article.
Aerosolized sulfated hyaluronan derivatives prolong the survival of K18 ACE2 mice infected with a lethal dose of SARS-CoV-2.
Pavan M, Fanti CD, Lucia AD, Canato E, Acquasaliente L, Sonvico F, Delgado J, Hicks A, Torrelles JB, Kulkarni V, Dwivedi V, Zanellato AM, Galesso D, Pasut G, Buttini F, Martinez-Sobrido L, Guarise C. Pavan M, et al. Eur J Pharm Sci. 2023 Aug 1;187:106489. doi: 10.1016/j.ejps.2023.106489. Epub 2023 Jun 11. Eur J Pharm Sci. 2023. PMID: 37311533 Free PMC article.
SARS-CoV-2 replication in airway epithelia requires motile cilia and microvillar reprogramming.
Wu CT, Lidsky PV, Xiao Y, Cheng R, Lee IT, Nakayama T, Jiang S, He W, Demeter J, Knight MG, Turn RE, Rojas-Hernandez LS, Ye C, Chiem K, Shon J, Martinez-Sobrido L, Bertozzi CR, Nolan GP, Nayak JV, Milla C, Andino R, Jackson PK. Wu CT, et al. Cell. 2023 Jan 5;186(1):112-130.e20. doi: 10.1016/j.cell.2022.11.030. Epub 2022 Dec 2. Cell. 2023. PMID: 36580912 Free PMC article.
312 results