Woll K - Search Results

1

Propofol directly binds and inhibits skeletal muscle ryanodine receptor 1 (RyR1).

Joseph TT, Bu W, Haji-Ghassemi O, Chen YS, Woll K, Allen PD, Brannigan G, van Petegem F, Eckenhoff RG. Joseph TT, et al. Among authors: woll k. bioRxiv [Preprint]. 2024 Jan 12:2024.01.10.575040. doi: 10.1101/2024.01.10.575040. bioRxiv. 2024. Update in: Br J Anaesth. 2024 Nov;133(5):1093-1100. doi: 10.1016/j.bja.2024.06.048 PMID: 38260485 Free PMC article. Updated. Preprint.

2

Mechanisms revealed through general anesthetic photolabeling.

Weiser BP, Woll KA, Dailey WP, Eckenhoff RG. Weiser BP, et al. Curr Anesthesiol Rep. 2014 Mar 1;4(1):57-66. doi: 10.1007/s40140-013-0040-7. Curr Anesthesiol Rep. 2014. PMID: 24563623 Free PMC article.

3

Role for the propofol hydroxyl in anesthetic protein target molecular recognition.

Woll KA, Weiser BP, Liang Q, Meng T, McKinstry-Wu A, Pinch B, Dailey WP, Gao WD, Covarrubias M, Eckenhoff RG. Woll KA, et al. ACS Chem Neurosci. 2015 Jun 17;6(6):927-35. doi: 10.1021/acschemneuro.5b00078. Epub 2015 Mar 30. ACS Chem Neurosci. 2015. PMID: 25799399 Free PMC article.

4

Macroscopic and macromolecular specificity of alkylphenol anesthetics for neuronal substrates.

Weiser BP, Hall MA, Weinbren NL, Woll KA, Dailey WP, Eckenhoff MF, Eckenhoff RG. Weiser BP, et al. Sci Rep. 2015 Apr 8;5:9695. doi: 10.1038/srep09695. Sci Rep. 2015. PMID: 25853337 Free PMC article.

5

A Novel Bifunctional Alkylphenol Anesthetic Allows Characterization of γ-Aminobutyric Acid, Type A (GABAA), Receptor Subunit Binding Selectivity in Synaptosomes.

Woll KA, Murlidaran S, Pinch BJ, Hénin J, Wang X, Salari R, Covarrubias M, Dailey WP, Brannigan G, Garcia BA, Eckenhoff RG. Woll KA, et al. J Biol Chem. 2016 Sep 23;291(39):20473-86. doi: 10.1074/jbc.M116.736975. Epub 2016 Jul 26. J Biol Chem. 2016. PMID: 27462076 Free PMC article.

6

Shedding Light on Anesthetic Mechanisms: Application of Photoaffinity Ligands.

Woll KA, Dailey WP, Brannigan G, Eckenhoff RG. Woll KA, et al. Anesth Analg. 2016 Nov;123(5):1253-1262. doi: 10.1213/ANE.0000000000001365. Anesth Analg. 2016. PMID: 27464974 Free PMC article. Review.

7

Photoaffinity Ligand for the Inhalational Anesthetic Sevoflurane Allows Mechanistic Insight into Potassium Channel Modulation.

Woll KA, Peng W, Liang Q, Zhi L, Jacobs JA, Maciunas L, Bhanu N, Garcia BA, Covarrubias M, Loll PJ, Dailey WP, Eckenhoff RG. Woll KA, et al. ACS Chem Biol. 2017 May 19;12(5):1353-1362. doi: 10.1021/acschembio.7b00222. Epub 2017 Apr 3. ACS Chem Biol. 2017. PMID: 28333442

8

Common general anesthetic propofol impairs kinesin processivity.

Bensel BM, Guzik-Lendrum S, Masucci EM, Woll KA, Eckenhoff RG, Gilbert SP. Bensel BM, et al. Proc Natl Acad Sci U S A. 2017 May 23;114(21):E4281-E4287. doi: 10.1073/pnas.1701482114. Epub 2017 May 8. Proc Natl Acad Sci U S A. 2017. PMID: 28484025 Free PMC article.

9

Sites Contributing to TRPA1 Activation by the Anesthetic Propofol Identified by Photoaffinity Labeling.

Woll KA, Skinner KA, Gianti E, Bhanu NV, Garcia BA, Carnevale V, Eckenhoff RG, Gaudet R. Woll KA, et al. Biophys J. 2017 Nov 21;113(10):2168-2172. doi: 10.1016/j.bpj.2017.08.040. Epub 2017 Sep 19. Biophys J. 2017. PMID: 28935134 Free PMC article.

10

Identification of binding sites contributing to volatile anesthetic effects on GABA type A receptors.

Woll KA, Zhou X, Bhanu NV, Garcia BA, Covarrubias M, Miller KW, Eckenhoff RG. Woll KA, et al. FASEB J. 2018 Aug;32(8):4172-4189. doi: 10.1096/fj.201701347R. Epub 2018 Mar 5. FASEB J. 2018. PMID: 29505303 Free PMC article.

Isoflurane and sevoflurane did not always share binding sites, which suggests an unexpected degree of selectivity.-Woll, K. A., Zhou, X., Bhanu, N. V., Garcia, B. A., Covarrubias, M., Miller, K. W., Eckenhoff, R. ...

Isoflurane and sevoflurane did not always share binding sites, which suggests an unexpected degree of selectivity.-Woll, K. A. …

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