Marks DS - Search Results

1

Deep generative modeling of the human proteome reveals over a hundred novel genes involved in rare genetic disorders.

Orenbuch R, Kollasch AW, Spinner HD, Shearer CA, Hopf TA, Franceschi D, Dias M, Frazer J, Marks DS. Orenbuch R, et al. Among authors: marks ds. Res Sq [Preprint]. 2024 Jan 4:rs.3.rs-3740259. doi: 10.21203/rs.3.rs-3740259/v1. Res Sq. 2024. PMID: 38260496 Free PMC article. Preprint.

2

Protein structure prediction from sequence variation.

Marks DS, Hopf TA, Sander C. Marks DS, et al. Nat Biotechnol. 2012 Nov;30(11):1072-80. doi: 10.1038/nbt.2419. Nat Biotechnol. 2012. PMID: 23138306 Free PMC article.

3

Protein design and variant prediction using autoregressive generative models.

Shin JE, Riesselman AJ, Kollasch AW, McMahon C, Simon E, Sander C, Manglik A, Kruse AC, Marks DS. Shin JE, et al. Among authors: marks ds. Nat Commun. 2021 Apr 23;12(1):2403. doi: 10.1038/s41467-021-22732-w. Nat Commun. 2021. PMID: 33893299 Free PMC article.

4

Disease variant prediction with deep generative models of evolutionary data.

Frazer J, Notin P, Dias M, Gomez A, Min JK, Brock K, Gal Y, Marks DS. Frazer J, et al. Among authors: marks ds. Nature. 2021 Nov;599(7883):91-95. doi: 10.1038/s41586-021-04043-8. Epub 2021 Oct 27. Nature. 2021. PMID: 34707284

5

Publisher Correction: Disease variant prediction with deep generative models of evolutionary data.

Frazer J, Notin P, Dias M, Gomez A, Min JK, Brock K, Gal Y, Marks DS. Frazer J, et al. Among authors: marks ds. Nature. 2022 Jan;601(7892):E7. doi: 10.1038/s41586-021-04207-6. Nature. 2022. PMID: 34921310 No abstract available.

6

Continuous evolution of user-defined genes at 1-million-times the genomic mutation rate.

Rix G, Williams RL, Spinner H, Hu VJ, Marks DS, Liu CC. Rix G, et al. Among authors: marks ds. bioRxiv [Preprint]. 2023 Nov 14:2023.11.13.566922. doi: 10.1101/2023.11.13.566922. bioRxiv. 2023. Update in: Science. 2024 Nov 8;386(6722):eadm9073. doi: 10.1126/science.adm9073 PMID: 38014077 Free PMC article. Updated. Preprint.

7

Deep generative modeling of the human proteome reveals over a hundred novel genes involved in rare genetic disorders.

Orenbuch R, Kollasch AW, Spinner HD, Shearer CA, Hopf TA, Franceschi D, Dias M, Frazer J, Marks DS. Orenbuch R, et al. Among authors: marks ds. medRxiv [Preprint]. 2023 Nov 28:2023.11.27.23299062. doi: 10.1101/2023.11.27.23299062. medRxiv. 2023. PMID: 38076790 Free PMC article. Preprint.

8

ProteinGym: Large-Scale Benchmarks for Protein Design and Fitness Prediction.

Notin P, Kollasch AW, Ritter D, van Niekerk L, Paul S, Spinner H, Rollins N, Shaw A, Weitzman R, Frazer J, Dias M, Franceschi D, Orenbuch R, Gal Y, Marks DS. Notin P, et al. Among authors: marks ds. bioRxiv [Preprint]. 2023 Dec 8:2023.12.07.570727. doi: 10.1101/2023.12.07.570727. bioRxiv. 2023. PMID: 38106144 Free PMC article. Preprint.

9

Protein 3D structure computed from evolutionary sequence variation.

Marks DS, Colwell LJ, Sheridan R, Hopf TA, Pagnani A, Zecchina R, Sander C. Marks DS, et al. PLoS One. 2011;6(12):e28766. doi: 10.1371/journal.pone.0028766. Epub 2011 Dec 7. PLoS One. 2011. PMID: 22163331 Free PMC article.

10

Three-dimensional structures of membrane proteins from genomic sequencing.

Hopf TA, Colwell LJ, Sheridan R, Rost B, Sander C, Marks DS. Hopf TA, et al. Among authors: marks ds. Cell. 2012 Jun 22;149(7):1607-21. doi: 10.1016/j.cell.2012.04.012. Epub 2012 May 10. Cell. 2012. PMID: 22579045 Free PMC article.

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