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Page 1
Asymmetric Synthesis and Biological Evaluation of Both Enantiomers of 5- and 6-Boronotryptophan as Potential Boron Delivery Agents for Boron Neutron Capture Therapy.
Retini M, Järvinen J, Bahrami K, Tampio J, Bartoccini F, Riihelä P, Pehkonen H, Värä A, Laitinen T, Huttunen KM, Rautio J, Piersanti G, Timonen JM. Retini M, et al. Among authors: pehkonen h. ACS Med Chem Lett. 2024 Nov 11;15(12):2121-2128. doi: 10.1021/acsmedchemlett.4c00241. eCollection 2024 Dec 12. ACS Med Chem Lett. 2024. PMID: 39691535 Free PMC article.
Liprin-α1 contributes to oncogenic MAPK signaling by counteracting ERK activity.
Pehkonen H, Filippou A, Väänänen J, Lindfors I, Vänttinen M, Ianevski P, Mäkelä A, Munne P, Klefström J, Toppila-Salmi S, Grénman R, Hagström J, Mäkitie AA, Karhemo PR, Monni O. Pehkonen H, et al. Mol Oncol. 2024 Mar;18(3):662-676. doi: 10.1002/1878-0261.13593. Epub 2024 Jan 24. Mol Oncol. 2024. PMID: 38264964 Free PMC article.
Liprin-α1 Expression in Tumor-Infiltrating Lymphocytes Associates with Improved Survival in Patients with HPV-Positive Oropharyngeal Squamous Cell Carcinoma.
Sjöblom A, Pehkonen H, Jouhi L, Monni O, Randén-Brady R, Karhemo PR, Tarkkanen J, Haglund C, Mattila P, Mäkitie A, Hagström J, Carpén T. Sjöblom A, et al. Among authors: pehkonen h. Head Neck Pathol. 2023 Sep;17(3):647-657. doi: 10.1007/s12105-023-01565-7. Epub 2023 Jun 19. Head Neck Pathol. 2023. PMID: 37335526 Free PMC article.
Liprins in oncogenic signaling and cancer cell adhesion.
Pehkonen H, de Curtis I, Monni O. Pehkonen H, et al. Oncogene. 2021 Nov;40(46):6406-6416. doi: 10.1038/s41388-021-02048-1. Epub 2021 Oct 15. Oncogene. 2021. PMID: 34654889 Free PMC article. Review.
Gene expression alterations in the cerebellum and granule neurons of Cstb(-/-) mouse are associated with early synaptic changes and inflammation.
Joensuu T, Tegelberg S, Reinmaa E, Segerstråle M, Hakala P, Pehkonen H, Korpi ER, Tyynelä J, Taira T, Hovatta I, Kopra O, Lehesjoki AE. Joensuu T, et al. Among authors: pehkonen h. PLoS One. 2014 Feb 27;9(2):e89321. doi: 10.1371/journal.pone.0089321. eCollection 2014. PLoS One. 2014. PMID: 24586687 Free PMC article.