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Interleukin-27 priming of T cells controls IL-17 production in trans via induction of the ligand PD-L1.
Hirahara K, Ghoreschi K, Yang XP, Takahashi H, Laurence A, Vahedi G, Sciumè G, Hall AO, Dupont CD, Francisco LM, Chen Q, Tanaka M, Kanno Y, Sun HW, Sharpe AH, Hunter CA, O'Shea JJ. Hirahara K, et al. Among authors: chen q. Immunity. 2012 Jun 29;36(6):1017-30. doi: 10.1016/j.immuni.2012.03.024. Epub 2012 Jun 21. Immunity. 2012. PMID: 22726954 Free PMC article.
Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling.
Ghoreschi K, Laurence A, Yang XP, Tato CM, McGeachy MJ, Konkel JE, Ramos HL, Wei L, Davidson TS, Bouladoux N, Grainger JR, Chen Q, Kanno Y, Watford WT, Sun HW, Eberl G, Shevach EM, Belkaid Y, Cua DJ, Chen W, O'Shea JJ. Ghoreschi K, et al. Among authors: chen q, chen w. Nature. 2010 Oct 21;467(7318):967-71. doi: 10.1038/nature09447. Nature. 2010. PMID: 20962846 Free PMC article.
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