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Establishing a synthetic orthogonal replication system enables accelerated evolution in E. coli.
Science. 2024 Jan 26;383(6681):421-426. doi: 10.1126/science.adk1281. Epub 2024 Jan 25.
Science. 2024.
PMID: 38271510
Refactored genetic codes enable bidirectional genetic isolation.
Zürcher JF, Robertson WE, Kappes T, Petris G, Elliott TS, Salmond GPC, Chin JW.
Zürcher JF, et al.
Science. 2022 Nov 4;378(6619):516-523. doi: 10.1126/science.add8943. Epub 2022 Oct 20.
Science. 2022.
PMID: 36264827
Free PMC article.
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Continuous synthesis of E. coli genome sections and Mb-scale human DNA assembly.
Zürcher JF, Kleefeldt AA, Funke LFH, Birnbaum J, Fredens J, Grazioli S, Liu KC, Spinck M, Petris G, Murat P, Rehm FBH, Sale JE, Chin JW.
Zürcher JF, et al.
Nature. 2023 Jul;619(7970):555-562. doi: 10.1038/s41586-023-06268-1. Epub 2023 Jun 28.
Nature. 2023.
PMID: 37380776
Free PMC article.
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