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19 results

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Page 1
Combination anti-PD-1 and anti-CTLA-4 therapy generates waves of clonal responses that include progenitor-exhausted CD8+ T cells.
Wang K, Coutifaris P, Brocks D, Wang G, Azar T, Solis S, Nandi A, Anderson S, Han N, Manne S, Kiner E, Sachar C, Lucas M, George S, Yan PK, Kier MW, Laughlin AI, Kothari S, Giles J, Mathew D, Ghinnagow R, Alanio C, Flowers A, Xu W, Tenney DJ, Xu X, Amaravadi RK, Karakousis GC, Schuchter LM, Buggert M, Oldridge D, Minn AJ, Blank C, Weber JS, Mitchell TC, Farwell MD, Herati RS, Huang AC. Wang K, et al. Among authors: kiner e. Cancer Cell. 2024 Sep 9;42(9):1582-1597.e10. doi: 10.1016/j.ccell.2024.08.007. Epub 2024 Aug 29. Cancer Cell. 2024. PMID: 39214097
Single-Cell View of Tumor Microenvironment Gradients in Pleural Mesothelioma.
Giotti B, Dolasia K, Zhao W, Cai P, Sweeney R, Merritt E, Kiner E, Kim GS, Bhagwat A, Nguyen T, Hegde S, Fitzgerald BG, Shroff S, Dawson T, Garcia-Barros M, Abdul-Ghafar J, Chen R, Gnjatic S, Soto A, Brody R, Kim-Schulze S, Chen Z, Beaumont KG, Merad M, Flores RM, Sebra RP, Horowitz A, Marron TU, Tocheva A, Wolf A, Tsankov AM. Giotti B, et al. Among authors: kiner e. Cancer Discov. 2024 Nov 1;14(11):2262-2278. doi: 10.1158/2159-8290.CD-23-0017. Cancer Discov. 2024. PMID: 38959428
Immunomodulatory effects and improved outcomes with cisplatin- versus carboplatin-based chemotherapy plus atezolizumab in urothelial cancer.
Galsky MD, Guan X, Rishipathak D, Rapaport AS, Shehata HM, Banchereau R, Yuen K, Varfolomeev E, Hu R, Han CJ, Li H, Liang Y, Vucic D, Wang L, Zhu J, Yu H, Herbst RH, Hajaj E, Kiner E, Bamias A, De Santis M, Davis ID, Arranz JÁ, Kikuchi E, Bernhard S, Williams P, Lee C, Mellman I, Sanjabi S, Johnston R, Black PC, Grande E, Mariathasan S. Galsky MD, et al. Among authors: kiner e. Cell Rep Med. 2024 Feb 20;5(2):101393. doi: 10.1016/j.xcrm.2024.101393. Epub 2024 Jan 26. Cell Rep Med. 2024. PMID: 38280376 Free PMC article. Clinical Trial.
Effective methods for bulk RNA-seq deconvolution using scnRNA-seq transcriptomes.
Cobos FA, Panah MJN, Epps J, Long X, Man TK, Chiu HS, Chomsky E, Kiner E, Krueger MJ, di Bernardo D, Voloch L, Molenaar J, van Hooff SR, Westermann F, Jansky S, Redell ML, Mestdagh P, Sumazin P. Cobos FA, et al. Among authors: kiner e. Genome Biol. 2023 Aug 1;24(1):177. doi: 10.1186/s13059-023-03016-6. Genome Biol. 2023. PMID: 37528411 Free PMC article.
A microRNA expression and regulatory element activity atlas of the mouse immune system.
Rose SA, Wroblewska A, Dhainaut M, Yoshida H, Shaffer JM, Bektesevic A, Ben-Zvi B, Rhoads A, Kim EY, Yu B, Lavin Y, Merad M, Buenrostro JD, Brown BD; Immunological Genome Consortium. Rose SA, et al. Nat Immunol. 2021 Jul;22(7):914-927. doi: 10.1038/s41590-021-00944-y. Epub 2021 Jun 7. Nat Immunol. 2021. PMID: 34099919 Free PMC article.
Targeting Treg cells with GITR activation alleviates resistance to immunotherapy in murine glioblastomas.
Amoozgar Z, Kloepper J, Ren J, Tay RE, Kazer SW, Kiner E, Krishnan S, Posada JM, Ghosh M, Mamessier E, Wong C, Ferraro GB, Batista A, Wang N, Badeaux M, Roberge S, Xu L, Huang P, Shalek AK, Fukumura D, Kim HJ, Jain RK. Amoozgar Z, et al. Among authors: kiner e. Nat Commun. 2021 May 11;12(1):2582. doi: 10.1038/s41467-021-22885-8. Nat Commun. 2021. PMID: 33976133 Free PMC article.
Multi-clonal SARS-CoV-2 neutralization by antibodies isolated from severe COVID-19 convalescent donors.
Mor M, Werbner M, Alter J, Safra M, Chomsky E, Lee JC, Hada-Neeman S, Polonsky K, Nowell CJ, Clark AE, Roitburd-Berman A, Ben-Shalom N, Navon M, Rafael D, Sharim H, Kiner E, Griffis ER, Gershoni JM, Kobiler O, Leibel SL, Zimhony O, Carlin AF, Yaari G, Dessau M, Gal-Tanamy M, Hagin D, Croker BA, Freund NT. Mor M, et al. Among authors: kiner e. PLoS Pathog. 2021 Feb 11;17(2):e1009165. doi: 10.1371/journal.ppat.1009165. eCollection 2021 Feb. PLoS Pathog. 2021. PMID: 33571304 Free PMC article.
Gut CD4+ T cell phenotypes are a continuum molded by microbes, not by TH archetypes.
Kiner E, Willie E, Vijaykumar B, Chowdhary K, Schmutz H, Chandler J, Schnell A, Thakore PI, LeGros G, Mostafavi S, Mathis D, Benoist C; Immunological Genome Project Consortium. Kiner E, et al. Nat Immunol. 2021 Feb;22(2):216-228. doi: 10.1038/s41590-020-00836-7. Epub 2021 Jan 18. Nat Immunol. 2021. PMID: 33462454 Free PMC article.
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