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Dual Chimeric Antigen Receptor T Cells Targeting CD38 and SLAMF7 with Independent Signaling Demonstrate Preclinical Efficacy and Safety in Multiple Myeloma.
Roders N, Nakid-Cordero C, Raineri F, Fayon M, Abecassis A, Choisy C, Nelson E, Maillard C, Garrick D, Talbot A, Fermand JP, Arnulf B, Bories JC. Roders N, et al. Among authors: choisy c. Cancer Immunol Res. 2024 Apr 2;12(4):478-490. doi: 10.1158/2326-6066.CIR-23-0839. Cancer Immunol Res. 2024. PMID: 38289260
CAR-T cells derived from multiple myeloma patients at diagnosis have improved cytotoxic functions compared to those produced at relapse or following daratumumab treatment.
Abecassis A, Roders N, Fayon M, Choisy C, Nelson E, Harel S, Royer B, Villesuzanne C, Talbot A, Garrick D, Goodhardt M, Fermand JP, Burbridge M, Arnulf B, Bories JC. Abecassis A, et al. Among authors: choisy c. EJHaem. 2022 Jun 21;3(3):970-974. doi: 10.1002/jha2.479. eCollection 2022 Aug. EJHaem. 2022. PMID: 36051036 Free PMC article.
The Sec61 translocon is a therapeutic vulnerability in multiple myeloma.
Domenger A, Choisy C, Baron L, Mayau V, Perthame E, Deriano L, Arnulf B, Bories JC, Dadaglio G, Demangel C. Domenger A, et al. Among authors: choisy c. EMBO Mol Med. 2022 Mar 7;14(3):e14740. doi: 10.15252/emmm.202114740. Epub 2022 Jan 11. EMBO Mol Med. 2022. PMID: 35014767 Free PMC article.
Age-Associated Decrease of the Histone Methyltransferase SUV39H1 in HSC Perturbs Heterochromatin and B Lymphoid Differentiation.
Djeghloul D, Kuranda K, Kuzniak I, Barbieri D, Naguibneva I, Choisy C, Bories JC, Dosquet C, Pla M, Vanneaux V, Socié G, Porteu F, Garrick D, Goodhardt M. Djeghloul D, et al. Among authors: choisy c. Stem Cell Reports. 2016 Jun 14;6(6):970-984. doi: 10.1016/j.stemcr.2016.05.007. Stem Cell Reports. 2016. PMID: 27304919 Free PMC article.
33 results