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IL-23R is a senescence-linked circulating and tissue biomarker of aging.
Carver CM, Rodriguez SL, Atkinson EJ, Dosch AJ, Asmussen NC, Gomez PT, Leitschuh EA, Espindola-Netto JM, Jeganathan KB, Whaley MG, Kamenecka TM, Baker DJ, Haak AJ, LeBrasseur NK, Schafer MJ. Carver CM, et al. Among authors: jeganathan kb. Nat Aging. 2024 Dec 10. doi: 10.1038/s43587-024-00752-7. Online ahead of print. Nat Aging. 2024. PMID: 39658621
Loss of HD-PTP function results in lipodystrophy, defective cellular signaling and altered lipid homeostasis.
Schultz DF, Davies BA, Payne JA, Martin CP, Minard AY, Childs BG, Zhang C, Jeganathan KB, Sturmlechner I, White TA, de Bruin A, Harkema L, Chen H, Davies MA, Jachim S, LeBrasseur NK, Piper RC, Li H, Baker DJ, van Deursen J, Billadeau DD, Katzmann DJ. Schultz DF, et al. Among authors: jeganathan kb. J Cell Sci. 2024 Sep 15;137(18):jcs262032. doi: 10.1242/jcs.262032. Epub 2024 Sep 27. J Cell Sci. 2024. PMID: 39155850
Liberal or Restrictive Transfusion Strategy in Patients with Traumatic Brain Injury.
Turgeon AF, Fergusson DA, Clayton L, Patton MP, Neveu X, Walsh TS, Docherty A, Malbouisson LM, Pili-Floury S, English SW, Zarychanski R, Moore L, Bonaventure PL, Laroche V, Verret M, Scales DC, Adhikari NKJ, Greenbaum J, Kramer A, Rey VG, Ball I, Khwaja K, Wise M, Harvey D, Lamontagne F, Chabanne R, Algird A, Krueper S, Pottecher J, Zeiler F, Rhodes J, Rigamonti A, Burns KEA, Marshall J, Griesdale DE, Sisconetto LS, Kutsogiannis DJ, Roger C, Green R, Boyd JG, Wright J, Charbonney E, Nair P, Astles T, Sy E, Hébert PC, Chassé M, Gomez A, Ramsay T, Taljaard M, Fox-Robichaud A, Tinmouth A, St-Onge M, Costerousse O, Lauzier F; HEMOTION Trial Investigators on behalf of the Canadian Critical Care Trials Group, the Canadian Perioperative Anesthesia Clinical Trials Group, and the Canadian Traumatic Brain Injury Research Consortium. Turgeon AF, et al. N Engl J Med. 2024 Aug 22;391(8):722-735. doi: 10.1056/NEJMoa2404360. Epub 2024 Jun 13. N Engl J Med. 2024. PMID: 38869931 Clinical Trial.
Hyperphosphorylated PTEN exerts oncogenic properties.
van Ree JH, Jeganathan KB, Fierro Velasco RO, Zhang C, Can I, Hamada M, Li H, Baker DJ, van Deursen JM. van Ree JH, et al. Among authors: jeganathan kb. Nat Commun. 2023 May 24;14(1):2983. doi: 10.1038/s41467-023-38740-x. Nat Commun. 2023. PMID: 37225693 Free PMC article.
69 results