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Aprepitant is a novel, selective activator of the K2P channel TRAAK.
McCoull D, Veale EL, Walsh Y, Byrom L, Avkiran T, Large JM, Vaitone E, Gaffey F, Jerman J, Mathie A, Wright PD. McCoull D, et al. Among authors: wright pd. Biochem Biophys Res Commun. 2022 Jan 15;588:41-46. doi: 10.1016/j.bbrc.2021.12.031. Epub 2021 Dec 14. Biochem Biophys Res Commun. 2022. PMID: 34942533 Free article.
Two-Pore Domain Potassium Channels as Drug Targets: Anesthesia and Beyond.
Mathie A, Veale EL, Cunningham KP, Holden RG, Wright PD. Mathie A, et al. Among authors: wright pd. Annu Rev Pharmacol Toxicol. 2021 Jan 6;61:401-420. doi: 10.1146/annurev-pharmtox-030920-111536. Epub 2020 Jul 17. Annu Rev Pharmacol Toxicol. 2021. PMID: 32679007
65 results