Liao C - Search Results

1

CRISPR-based screening of small RNA modulators of bile susceptibility in Bacteroides thetaiotaomicron.

Prezza G, Liao C, Reichardt S, Beisel CL, Westermann AJ. Prezza G, et al. Among authors: liao c. Proc Natl Acad Sci U S A. 2024 Feb 6;121(6):e2311323121. doi: 10.1073/pnas.2311323121. Epub 2024 Jan 31. Proc Natl Acad Sci U S A. 2024. PMID: 38294941 Free PMC article.

2

The tracrRNA in CRISPR Biology and Technologies.

Liao C, Beisel CL. Liao C, et al. Annu Rev Genet. 2021 Nov 23;55:161-181. doi: 10.1146/annurev-genet-071719-022559. Epub 2021 Aug 20. Annu Rev Genet. 2021. PMID: 34416117 Free PMC article. Review.

3

The Francisella novicida Cas12a is sensitive to the structure downstream of the terminal repeat in CRISPR arrays.

Liao C, Slotkowski RA, Achmedov T, Beisel CL. Liao C, et al. RNA Biol. 2019 Apr;16(4):404-412. doi: 10.1080/15476286.2018.1526537. Epub 2018 Oct 12. RNA Biol. 2019. PMID: 30252595 Free PMC article.

4

The Acidaminococcus sp. Cas12a nuclease recognizes GTTV and GCTV as non-canonical PAMs.

Jacobsen T, Liao C, Beisel CL. Jacobsen T, et al. Among authors: liao c. FEMS Microbiol Lett. 2019 Apr 1;366(8):fnz085. doi: 10.1093/femsle/fnz085. FEMS Microbiol Lett. 2019. PMID: 31004485 Free PMC article.

5

CRATES: A one-step assembly method for Class 2 CRISPR arrays.

Liao C, Slotkowski RA, Beisel CL. Liao C, et al. Methods Enzymol. 2019;629:493-511. doi: 10.1016/bs.mie.2019.04.011. Epub 2019 Aug 5. Methods Enzymol. 2019. PMID: 31727255

6

Characterization of Cas12a nucleases reveals diverse PAM profiles between closely-related orthologs.

Jacobsen T, Ttofali F, Liao C, Manchalu S, Gray BN, Beisel CL. Jacobsen T, et al. Among authors: liao c. Nucleic Acids Res. 2020 Jun 4;48(10):5624-5638. doi: 10.1093/nar/gkaa272. Nucleic Acids Res. 2020. PMID: 32329776 Free PMC article.

7

Sequence-independent RNA sensing and DNA targeting by a split domain CRISPR-Cas12a gRNA switch.

Collins SP, Rostain W, Liao C, Beisel CL. Collins SP, et al. Among authors: liao c. Nucleic Acids Res. 2021 Mar 18;49(5):2985-2999. doi: 10.1093/nar/gkab100. Nucleic Acids Res. 2021. PMID: 33619539 Free PMC article.

8

Spacer prioritization in CRISPR-Cas9 immunity is enabled by the leader RNA.

Liao C, Sharma S, Svensson SL, Kibe A, Weinberg Z, Alkhnbashi OS, Bischler T, Backofen R, Caliskan N, Sharma CM, Beisel CL. Liao C, et al. Nat Microbiol. 2022 Apr;7(4):530-541. doi: 10.1038/s41564-022-01074-3. Epub 2022 Mar 21. Nat Microbiol. 2022. PMID: 35314780 Free PMC article.

9

The miniature CRISPR-Cas12m effector binds DNA to block transcription.

Wu WY, Mohanraju P, Liao C, Adiego-Pérez B, Creutzburg SCA, Makarova KS, Keessen K, Lindeboom TA, Khan TS, Prinsen S, Joosten R, Yan WX, Migur A, Laffeber C, Scott DA, Lebbink JHG, Koonin EV, Beisel CL, van der Oost J. Wu WY, et al. Among authors: liao c. Mol Cell. 2022 Dec 1;82(23):4487-4502.e7. doi: 10.1016/j.molcel.2022.11.003. Epub 2022 Nov 24. Mol Cell. 2022. PMID: 36427491 Free article.

10

Shortened CRISPR-Cas9 arrays enable multiplexed gene targeting in bacteria from a smaller DNA footprint.

Gawlitt S, Liao C, Achmedov T, Beisel CL. Gawlitt S, et al. Among authors: liao c. RNA Biol. 2023 Jan;20(1):666-680. doi: 10.1080/15476286.2023.2247247. RNA Biol. 2023. PMID: 37654098 Free PMC article.

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