Hilvert D - Search Results

1

High-throughput reprogramming of an NRPS condensation domain.

Folger IB, Frota NF, Pistofidis A, Niquille DL, Hansen DA, Schmeing TM, Hilvert D. Folger IB, et al. Among authors: hilvert d. Nat Chem Biol. 2024 Jun;20(6):761-769. doi: 10.1038/s41589-023-01532-x. Epub 2024 Feb 2. Nat Chem Biol. 2024. PMID: 38308044 Free PMC article.

2

Evolution of a designed retro-aldolase leads to complete active site remodeling.

Giger L, Caner S, Obexer R, Kast P, Baker D, Ban N, Hilvert D. Giger L, et al. Among authors: hilvert d. Nat Chem Biol. 2013 Aug;9(8):494-8. doi: 10.1038/nchembio.1276. Epub 2013 Jun 9. Nat Chem Biol. 2013. PMID: 23748672 Free PMC article.

3

Reprogramming nonribosomal peptide synthetases for "clickable" amino acids.

Kries H, Wachtel R, Pabst A, Wanner B, Niquille D, Hilvert D. Kries H, et al. Among authors: hilvert d. Angew Chem Int Ed Engl. 2014 Sep 15;53(38):10105-8. doi: 10.1002/anie.201405281. Epub 2014 Jul 31. Angew Chem Int Ed Engl. 2014. PMID: 25081643

4

A subdomain swap strategy for reengineering nonribosomal peptides.

Kries H, Niquille DL, Hilvert D. Kries H, et al. Among authors: hilvert d. Chem Biol. 2015 May 21;22(5):640-8. doi: 10.1016/j.chembiol.2015.04.015. Chem Biol. 2015. PMID: 26000750

5

Nonribosomal biosynthesis of backbone-modified peptides.

Niquille DL, Hansen DA, Mori T, Fercher D, Kries H, Hilvert D. Niquille DL, et al. Among authors: hilvert d. Nat Chem. 2018 Mar;10(3):282-287. doi: 10.1038/nchem.2891. Epub 2017 Nov 20. Nat Chem. 2018. PMID: 29461527

6

Evolution of a highly active and enantiospecific metalloenzyme from short peptides.

Studer S, Hansen DA, Pianowski ZL, Mittl PRE, Debon A, Guffy SL, Der BS, Kuhlman B, Hilvert D. Studer S, et al. Among authors: hilvert d. Science. 2018 Dec 14;362(6420):1285-1288. doi: 10.1126/science.aau3744. Science. 2018. PMID: 30545884

7

Biosynthetic Functionalization of Nonribosomal Peptides.

Niquille DL, Folger IB, Basler S, Hilvert D. Niquille DL, et al. Among authors: hilvert d. J Am Chem Soc. 2021 Feb 24;143(7):2736-2740. doi: 10.1021/jacs.1c00925. Epub 2021 Feb 11. J Am Chem Soc. 2021. PMID: 33570948

8

Structures and function of the amino acid polymerase cyanophycin synthetase.

Sharon I, Haque AS, Grogg M, Lahiri I, Seebach D, Leschziner AE, Hilvert D, Schmeing TM. Sharon I, et al. Among authors: hilvert d. Nat Chem Biol. 2021 Oct;17(10):1101-1110. doi: 10.1038/s41589-021-00854-y. Epub 2021 Aug 12. Nat Chem Biol. 2021. PMID: 34385683

9

Structure and Function of the β-Asp-Arg Polymerase Cyanophycin Synthetase 2.

Sharon I, Grogg M, Hilvert D, Schmeing TM. Sharon I, et al. Among authors: hilvert d. ACS Chem Biol. 2022 Mar 18;17(3):670-679. doi: 10.1021/acschembio.1c01007. Epub 2022 Feb 18. ACS Chem Biol. 2022. PMID: 35179888

10

A cryptic third active site in cyanophycin synthetase creates primers for polymerization.

Sharon I, Pinus S, Grogg M, Moitessier N, Hilvert D, Schmeing TM. Sharon I, et al. Among authors: hilvert d. Nat Commun. 2022 Jul 7;13(1):3923. doi: 10.1038/s41467-022-31542-7. Nat Commun. 2022. PMID: 35798723 Free PMC article.

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