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Pharmacological degradation of ATR induces antiproliferative DNA replication stress in leukemic cells.
Mol Oncol. 2024 Aug;18(8):1958-1965. doi: 10.1002/1878-0261.13638. Epub 2024 Mar 22.
Mol Oncol. 2024.
PMID: 38520049
Free PMC article.
Design, synthesis, and biological characterization of proteolysis targeting chimera (PROTACs) for the ataxia telangiectasia and RAD3-related (ATR) kinase.
Alfayomy AM, Ashry R, Kansy AG, Sarnow AC, Erdmann F, Schmidt M, Krämer OH, Sippl W.
Alfayomy AM, et al. Among authors: kansy ag.
Eur J Med Chem. 2024 Mar 5;267:116167. doi: 10.1016/j.ejmech.2024.116167. Epub 2024 Jan 29.
Eur J Med Chem. 2024.
PMID: 38308949
Free article.
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Novel hydroxamic acid derivative induces apoptosis and constrains autophagy in leukemic cells.
Fischer MA, Mustafa AM, Hausmann K, Ashry R, Kansy AG, Liebl MC, Brachetti C, Piée-Staffa A, Zessin M, Ibrahim HS, Hofmann TG, Schutkowski M, Sippl W, Krämer OH.
Fischer MA, et al. Among authors: kansy ag.
J Adv Res. 2024 Jun;60:201-214. doi: 10.1016/j.jare.2023.07.005. Epub 2023 Jul 17.
J Adv Res. 2024.
PMID: 37467961
Free PMC article.
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