Vrba J - Search Results

1

Phytocannabinoids and gingival inflammation: Preclinical findings and a placebo-controlled double-blind randomized clinical trial with cannabidiol.

Jirasek P, Jusku A, Frankova J, Urbankova M, Diabelko D, Ruzicka F, Papouskova B, Chytilova K, Vrba J, Havlasek J, Langova K, Storch J, Voborna I, Simanek V, Vacek J. Jirasek P, et al. Among authors: vrba j. J Periodontal Res. 2024 Jun;59(3):468-479. doi: 10.1111/jre.13234. Epub 2024 Feb 5. J Periodontal Res. 2024. PMID: 38311974 Clinical Trial.

2

Hepatic biotransformation of non-psychotropic phytocannabinoids and activity screening on cytochromes P450 and UDP-glucuronosyltransferases.

Havlasek J, Vrba J, Zatloukalova M, Papouskova B, Modriansky M, Storch J, Vacek J. Havlasek J, et al. Among authors: vrba j. Toxicol Appl Pharmacol. 2023 Oct 1;476:116654. doi: 10.1016/j.taap.2023.116654. Epub 2023 Aug 12. Toxicol Appl Pharmacol. 2023. PMID: 37574147

3

Quercetin, quercetin glycosides and taxifolin differ in their ability to induce AhR activation and CYP1A1 expression in HepG2 cells.

Vrba J, Kren V, Vacek J, Papouskova B, Ulrichova J. Vrba J, et al. Phytother Res. 2012 Nov;26(11):1746-52. doi: 10.1002/ptr.4637. Epub 2012 Mar 15. Phytother Res. 2012. PMID: 22422552

4

Cytotoxicity of hexahelicene and its effect on the aryl hydrocarbon receptor pathway.

Vrba J, Roubalova L, Cirkva V, Storch J, Vacek J. Vrba J, et al. Toxicol In Vitro. 2019 Jun;57:105-109. doi: 10.1016/j.tiv.2019.02.020. Epub 2019 Feb 26. Toxicol In Vitro. 2019. PMID: 30822459

5

Sulfation modulates the cell uptake, antiradical activity and biological effects of flavonoids in vitro: An examination of quercetin, isoquercitrin and taxifolin.

Roubalová L, Purchartová K, Papoušková B, Vacek J, Křen V, Ulrichová J, Vrba J. Roubalová L, et al. Among authors: vrba j. Bioorg Med Chem. 2015 Sep 1;23(17):5402-9. doi: 10.1016/j.bmc.2015.07.055. Epub 2015 Jul 29. Bioorg Med Chem. 2015. PMID: 26260337

6

Semisynthetic flavonoid 7-O-galloylquercetin activates Nrf2 and induces Nrf2-dependent gene expression in RAW264.7 and Hepa1c1c7 cells.

Roubalová L, Biedermann D, Papoušková B, Vacek J, Kuzma M, Křen V, Ulrichová J, Dinkova-Kostova AT, Vrba J. Roubalová L, et al. Among authors: vrba j. Chem Biol Interact. 2016 Dec 25;260:58-66. doi: 10.1016/j.cbi.2016.10.015. Epub 2016 Oct 21. Chem Biol Interact. 2016. PMID: 27777014 Free PMC article.

7

Cubosomal lipid formulation of nitroalkene fatty acids: Preparation, stability and biological effects.

Zatloukalová M, Jedinák L, Riman D, Franková J, Novák D, Cytryniak A, Nazaruk E, Bilewicz R, Vrba J, Papoušková B, Kabeláč M, Vacek J. Zatloukalová M, et al. Among authors: vrba j. Redox Biol. 2021 Oct;46:102097. doi: 10.1016/j.redox.2021.102097. Epub 2021 Aug 8. Redox Biol. 2021. PMID: 34418599 Free PMC article.

8

A novel semisynthetic flavonoid 7-O-galloyltaxifolin upregulates heme oxygenase-1 in RAW264.7 cells via MAPK/Nrf2 pathway.

Vrba J, Gažák R, Kuzma M, Papoušková B, Vacek J, Weiszenstein M, Křen V, Ulrichová J. Vrba J, et al. J Med Chem. 2013 Feb 14;56(3):856-66. doi: 10.1021/jm3013344. Epub 2013 Jan 18. J Med Chem. 2013. PMID: 23294286

9

LC-MS metabolic study on quercetin and taxifolin galloyl esters using human hepatocytes as toxicity and biotransformation in vitro cell model.

Vacek J, Papoušková B, Vrba J, Zatloukalová M, Křen V, Ulrichová J. Vacek J, et al. Among authors: vrba j. J Pharm Biomed Anal. 2013 Dec;86:135-42. doi: 10.1016/j.jpba.2013.07.045. Epub 2013 Aug 14. J Pharm Biomed Anal. 2013. PMID: 24008144

10

Biotransformation of flavonols and taxifolin in hepatocyte in vitro systems as determined by liquid chromatography with various stationary phases and electrospray ionization-quadrupole time-of-flight mass spectrometry.

Vacek J, Papoušková B, Kosina P, Vrba J, Křen V, Ulrichová J. Vacek J, et al. Among authors: vrba j. J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Jun 15;899:109-15. doi: 10.1016/j.jchromb.2012.05.009. Epub 2012 May 14. J Chromatogr B Analyt Technol Biomed Life Sci. 2012. PMID: 22664057

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