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Page 1
MYC targeting by OMO-103 in solid tumors: a phase 1 trial.
Garralda E, Beaulieu ME, Moreno V, Casacuberta-Serra S, Martínez-Martín S, Foradada L, Alonso G, Massó-Vallés D, López-Estévez S, Jauset T, Corral de la Fuente E, Doger B, Hernández T, Perez-Lopez R, Arqués O, Castillo Cano V, Morales J, Whitfield JR, Niewel M, Soucek L, Calvo E. Garralda E, et al. Among authors: foradada l. Nat Med. 2024 Mar;30(3):762-771. doi: 10.1038/s41591-024-02805-1. Epub 2024 Feb 6. Nat Med. 2024. PMID: 38321218 Free PMC article. Clinical Trial.
Intrinsic cell-penetrating activity propels Omomyc from proof of concept to viable anti-MYC therapy.
Beaulieu ME, Jauset T, Massó-Vallés D, Martínez-Martín S, Rahl P, Maltais L, Zacarias-Fluck MF, Casacuberta-Serra S, Serrano Del Pozo E, Fiore C, Foradada L, Cano VC, Sánchez-Hervás M, Guenther M, Romero Sanz E, Oteo M, Tremblay C, Martín G, Letourneau D, Montagne M, Morcillo Alonso MÁ, Whitfield JR, Lavigne P, Soucek L. Beaulieu ME, et al. Among authors: foradada l. Sci Transl Med. 2019 Mar 20;11(484):eaar5012. doi: 10.1126/scitranslmed.aar5012. Sci Transl Med. 2019. PMID: 30894502 Free PMC article.
MYC Inhibition Halts Metastatic Breast Cancer Progression by Blocking Growth, Invasion, and Seeding.
Massó-Vallés D, Beaulieu ME, Jauset T, Giuntini F, Zacarías-Fluck MF, Foradada L, Martínez-Martín S, Serrano E, Martín-Fernández G, Casacuberta-Serra S, Castillo Cano V, Kaur J, López-Estévez S, Morcillo MÁ, Alzrigat M, Mahmoud L, Luque-García A, Escorihuela M, Guzman M, Arribas J, Serra V, Larsson LG, Whitfield JR, Soucek L. Massó-Vallés D, et al. Among authors: foradada l. Cancer Res Commun. 2022 Feb 21;2(2):110-130. doi: 10.1158/2767-9764.CRC-21-0103. eCollection 2022 Feb. Cancer Res Commun. 2022. PMID: 36860495 Free PMC article.
Reducing MYC's transcriptional footprint unveils a good prognostic gene signature in melanoma.
Zacarías-Fluck MF, Massó-Vallés D, Giuntini F, González-Larreategui Í, Kaur J, Casacuberta-Serra S, Jauset T, Martínez-Martín S, Martín-Fernández G, Serrano Del Pozo E, Foradada L, Grueso J, Nonell L, Beaulieu ME, Whitfield JR, Soucek L. Zacarías-Fluck MF, et al. Among authors: foradada l. Genes Dev. 2023 Apr 1;37(7-8):303-320. doi: 10.1101/gad.350078.122. Epub 2023 Apr 6. Genes Dev. 2023. PMID: 37024284 Free PMC article.
BET inhibition is an effective approach against KRAS-driven PDAC and NSCLC.
Jauset T, Massó-Vallés D, Martínez-Martín S, Beaulieu ME, Foradada L, Fiorentino FP, Yokota J, Haendler B, Siegel S, Whitfield JR, Soucek L. Jauset T, et al. Among authors: foradada l. Oncotarget. 2018 Apr 10;9(27):18734-18746. doi: 10.18632/oncotarget.24648. eCollection 2018 Apr 10. Oncotarget. 2018. PMID: 29721157 Free PMC article.
In Vivo Antitumor and Antimetastatic Efficacy of a Polyacetal-Based Paclitaxel Conjugate for Prostate Cancer Therapy.
Fernández Y, Movellan J, Foradada L, Giménez V, García-Aranda N, Mancilla S, Armiñán A, Borgos SE, Hyldbakk A, Bogdanska A, Gobbo OL, Prina-Mello A, Ponti J, Calzolai L, Zagorodko O, Gallon E, Niño-Pariente A, Paul A, Schwartz S Jr, Abasolo I, Vicent MJ. Fernández Y, et al. Among authors: foradada l. Adv Healthc Mater. 2022 Apr;11(7):e2101544. doi: 10.1002/adhm.202101544. Epub 2021 Nov 10. Adv Healthc Mater. 2022. PMID: 34706167
Engineering pH-Sensitive Stable Nanovesicles for Delivery of MicroRNA Therapeutics.
Boloix A, Feiner-Gracia N, Köber M, Repetto J, Pascarella R, Soriano A, Masanas M, Segovia N, Vargas-Nadal G, Merlo-Mas J, Danino D, Abutbul-Ionita I, Foradada L, Roma J, Córdoba A, Sala S, de Toledo JS, Gallego S, Veciana J, Albertazzi L, Segura MF, Ventosa N. Boloix A, et al. Among authors: foradada l. Small. 2022 Jan;18(3):e2101959. doi: 10.1002/smll.202101959. Epub 2021 Nov 16. Small. 2022. PMID: 34786859 Free article.
15 results