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Targeting CD33+ Acute Myeloid Leukemia with GLK-33, a Lintuzumab-Auristatin Conjugate with a Wide Therapeutic Window.
Mol Cancer Ther. 2024 Aug 1;23(8):1073-1083. doi: 10.1158/1535-7163.MCT-23-0720.
Mol Cancer Ther. 2024.
PMID: 38561023
Trastuzumab-MMAU Antibody-Auristatin Conjugates: Valine-Glucoserine Linker with Stabilized Maleimide Conjugation Improves In Vivo Efficacy and Tolerability.
Goldberg SD, Satomaa T, Aina O, Aitio O, Burke K, Dudkin V, Geist B, Irrechukwu O, Hänninen AL, Heiskanen A, Helin J, Hiltunen JO, Kinyamu-Akunda J, Klein DM, Kohli N, Kotiranta T, Lähteenmäki T, Niemelä R, Pitkänen V, Pynnönen H, Rittase W, Wiley K, Zhou J, Saarinen J.
Goldberg SD, et al. Among authors: kotiranta t.
Mol Cancer Ther. 2024 Nov 4;23(11):1530-1543. doi: 10.1158/1535-7163.MCT-23-0591.
Mol Cancer Ther. 2024.
PMID: 38324296
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Hydrophilic Auristatin Glycoside Payload Enables Improved Antibody-Drug Conjugate Efficacy and Biocompatibility.
Satomaa T, Pynnönen H, Vilkman A, Kotiranta T, Pitkänen V, Heiskanen A, Herpers B, Price LS, Helin J, Saarinen J.
Satomaa T, et al. Among authors: kotiranta t.
Antibodies (Basel). 2018 Mar 22;7(2):15. doi: 10.3390/antib7020015.
Antibodies (Basel). 2018.
PMID: 31544867
Free PMC article.
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