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The conformational landscape of human transthyretin revealed by cryo-EM.
Basanta B, Nugroho K, Yan NL, Kline GM, Powers ET, Tsai FJ, Wu M, Hansel-Harris A, Chen JS, Forli S, Kelly JW, Lander GC. Basanta B, et al. Among authors: powers et. bioRxiv [Preprint]. 2024 Jan 23:2024.01.23.576879. doi: 10.1101/2024.01.23.576879. bioRxiv. 2024. PMID: 38328110 Free PMC article. Preprint.
Divergent Proteome Reactivity Influences Arm-Selective Activation of Pharmacological Endoplasmic Reticulum Proteostasis Regulators.
Kline GM, Paxman RJ, Lin CY, Madrazo N, Grandjean JM, Lee K, Nugroho K, Powers ET, Wiseman RL, Kelly JW. Kline GM, et al. Among authors: powers et. bioRxiv [Preprint]. 2023 Jan 17:2023.01.16.524237. doi: 10.1101/2023.01.16.524237. bioRxiv. 2023. Update in: ACS Chem Biol. 2023 Aug 18;18(8):1719-1729. doi: 10.1021/acschembio.3c00042 PMID: 36712115 Free PMC article. Updated. Preprint.
Divergent Proteome Reactivity Influences Arm-Selective Activation of the Unfolded Protein Response by Pharmacological Endoplasmic Reticulum Proteostasis Regulators.
Kline GM, Paxman RJ, Lin CY, Madrazo N, Yoon L, Grandjean JMD, Lee K, Nugroho K, Powers ET, Wiseman RL, Kelly JW. Kline GM, et al. Among authors: powers et. ACS Chem Biol. 2023 Aug 18;18(8):1719-1729. doi: 10.1021/acschembio.3c00042. Epub 2023 Jul 31. ACS Chem Biol. 2023. PMID: 37523656 Free PMC article.
Current and future treatment of amyloid diseases.
Ankarcrona M, Winblad B, Monteiro C, Fearns C, Powers ET, Johansson J, Westermark GT, Presto J, Ericzon BG, Kelly JW. Ankarcrona M, et al. Among authors: powers et. J Intern Med. 2016 Aug;280(2):177-202. doi: 10.1111/joim.12506. Epub 2016 May 10. J Intern Med. 2016. PMID: 27165517 Free PMC article. Review.
"Inverse Drug Discovery" Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates.
Mortenson DE, Brighty GJ, Plate L, Bare G, Chen W, Li S, Wang H, Cravatt BF, Forli S, Powers ET, Sharpless KB, Wilson IA, Kelly JW. Mortenson DE, et al. Among authors: powers et. J Am Chem Soc. 2018 Jan 10;140(1):200-210. doi: 10.1021/jacs.7b08366. Epub 2017 Dec 21. J Am Chem Soc. 2018. PMID: 29265822 Free PMC article.
105 results