Engelman AN - Search Results

1

Oligomeric HIV-1 Integrase Structures Reveal Functional Plasticity for Intasome Assembly and RNA Binding.

Jing T, Shan Z, Dinh T, Biswas A, Jang S, Greenwood J, Li M, Zhang Z, Gray G, Shin HJ, Zhou B, Passos D, Aiyer S, Li Z, Craigie R, Engelman AN, Kvaratskhelia M, Lyumkis D. Jing T, et al. Among authors: engelman an. bioRxiv [Preprint]. 2024 Jan 27:2024.01.26.577436. doi: 10.1101/2024.01.26.577436. bioRxiv. 2024. PMID: 38328132 Free PMC article. Preprint.

2

Identification of conserved amino acid residues critical for human immunodeficiency virus type 1 integrase function in vitro.

Engelman A, Craigie R. Engelman A, et al. J Virol. 1992 Nov;66(11):6361-9. doi: 10.1128/JVI.66.11.6361-6369.1992. J Virol. 1992. PMID: 1404595 Free PMC article.

3

HIV-1 DNA integration: mechanism of viral DNA cleavage and DNA strand transfer.

Engelman A, Mizuuchi K, Craigie R. Engelman A, et al. Cell. 1991 Dec 20;67(6):1211-21. doi: 10.1016/0092-8674(91)90297-c. Cell. 1991. PMID: 1760846

4

Efficient magnesium-dependent human immunodeficiency virus type 1 integrase activity.

Engelman A, Craigie R. Engelman A, et al. J Virol. 1995 Sep;69(9):5908-11. doi: 10.1128/JVI.69.9.5908-5911.1995. J Virol. 1995. PMID: 7637039 Free PMC article.

5

The core and carboxyl-terminal domains of the integrase protein of human immunodeficiency virus type 1 each contribute to nonspecific DNA binding.

Engelman A, Hickman AB, Craigie R. Engelman A, et al. J Virol. 1994 Sep;68(9):5911-7. doi: 10.1128/JVI.68.9.5911-5917.1994. J Virol. 1994. PMID: 8057470 Free PMC article.

6

Identification of discrete functional domains of HIV-1 integrase and their organization within an active multimeric complex.

Engelman A, Bushman FD, Craigie R. Engelman A, et al. EMBO J. 1993 Aug;12(8):3269-75. doi: 10.1002/j.1460-2075.1993.tb05996.x. EMBO J. 1993. PMID: 8344264 Free PMC article.

7

A soluble active mutant of HIV-1 integrase: involvement of both the core and carboxyl-terminal domains in multimerization.

Jenkins TM, Engelman A, Ghirlando R, Craigie R. Jenkins TM, et al. J Biol Chem. 1996 Mar 29;271(13):7712-8. doi: 10.1074/jbc.271.13.7712. J Biol Chem. 1996. PMID: 8631811 Free article.

8

Critical contacts between HIV-1 integrase and viral DNA identified by structure-based analysis and photo-crosslinking.

Jenkins TM, Esposito D, Engelman A, Craigie R. Jenkins TM, et al. EMBO J. 1997 Nov 17;16(22):6849-59. doi: 10.1093/emboj/16.22.6849. EMBO J. 1997. PMID: 9362498 Free PMC article.

9

Subunit-specific protein footprinting reveals significant structural rearrangements and a role for N-terminal Lys-14 of HIV-1 Integrase during viral DNA binding.

Zhao Z, McKee CJ, Kessl JJ, Santos WL, Daigle JE, Engelman A, Verdine G, Kvaratskhelia M. Zhao Z, et al. J Biol Chem. 2008 Feb 29;283(9):5632-41. doi: 10.1074/jbc.M705241200. Epub 2007 Dec 19. J Biol Chem. 2008. PMID: 18093980 Free PMC article.

10

Dynamic modulation of HIV-1 integrase structure and function by cellular lens epithelium-derived growth factor (LEDGF) protein.

McKee CJ, Kessl JJ, Shkriabai N, Dar MJ, Engelman A, Kvaratskhelia M. McKee CJ, et al. J Biol Chem. 2008 Nov 14;283(46):31802-12. doi: 10.1074/jbc.M805843200. Epub 2008 Sep 18. J Biol Chem. 2008. PMID: 18801737 Free PMC article.

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