Rawlings DJ - Search Results

1

The IFIH1-A946T risk variant promotes diabetes in a sex-dependent manner.

Stock AJ, Gonzalez-Paredes P, Previato de Almeida L, Kosanke SD, Chetlur S, Budde H, Wakenight P, Zwingman TA, Rosen AB, Allenspach E, Millen KJ, Buckner JH, Rawlings DJ, Gorman JA. Stock AJ, et al. Among authors: rawlings dj. bioRxiv [Preprint]. 2024 Jan 23:2024.01.20.576482. doi: 10.1101/2024.01.20.576482. bioRxiv. 2024. Update in: Front Immunol. 2024 Feb 29;15:1349601. doi: 10.3389/fimmu.2024.1349601 PMID: 38328221 Free PMC article. Updated. Preprint.

2

Activated PI3Kδ specifically perturbs mouse Treg homeostasis and function leading to immune dysregulation.

Singh AK, Qureshah FA, Drow T, Hou B, Rawlings DJ. Singh AK, et al. Among authors: rawlings dj. bioRxiv [Preprint]. 2023 Dec 23:2023.12.21.569665. doi: 10.1101/2023.12.21.569665. bioRxiv. 2023. Update in: J Immunol. 2024 Jul 15;213(2):135-147. doi: 10.4049/jimmunol.2400032 PMID: 38187650 Free PMC article. Updated. Preprint.

3

IL-4 downregulates BCL6 to promote memory B cell selection in germinal centers.

Shehata L, Thouvenel CD, Hondowicz BD, Pew LA, Rawlings DJ, Choi J, Pepper M. Shehata L, et al. Among authors: rawlings dj. bioRxiv [Preprint]. 2023 Oct 4:2023.01.26.525749. doi: 10.1101/2023.01.26.525749. bioRxiv. 2023. Update in: Immunity. 2024 Apr 9;57(4):843-858.e5. doi: 10.1016/j.immuni.2024.02.018 PMID: 36747852 Free PMC article. Updated. Preprint.

4

Targeting human plasma cells using small molecule regulated BCMA CAR T cells eliminates circulating antibodies in humanized mice.

Honaker Y, Gruber D, Jacobs C, Yu-Hong Cheng R, Patel S, Galvan CZ, Khan IF, Zhou K, Sommer K, Astrakhan A, Cook PJ, James RG, Rawlings DJ. Honaker Y, et al. Among authors: rawlings dj. Mol Ther. 2024 Dec 12:S1525-0016(24)00817-7. doi: 10.1016/j.ymthe.2024.12.018. Online ahead of print. Mol Ther. 2024. PMID: 39673129

5

Identification of a novel PDC-E2 epitope in primary biliary cholangitis: Application for engineered Treg therapy.

Tewari R, Yang SJ, McClain ED, Hu A, Mortensen E, DeSchmidt A, Chen J, Kancharla A, Singh AK, James EA, Burman BE, Siddique A, Rawlings DJ, Patel C, Cerosaletti K, Buckner JH. Tewari R, et al. Among authors: rawlings dj. J Autoimmun. 2024 Dec;149:103327. doi: 10.1016/j.jaut.2024.103327. Epub 2024 Oct 30. J Autoimmun. 2024. PMID: 39476446

6

Generation, expansion, gene delivery, and single-cell profiling in rhesus macaque plasma B cells.

Yu-Hong Cheng R, Helmers AE, Kreuser S, Dahl N, Honaker Y, Lopez C, Rawlings DJ, James RG. Yu-Hong Cheng R, et al. Among authors: rawlings dj. Cell Rep Methods. 2024 Oct 21;4(10):100878. doi: 10.1016/j.crmeth.2024.100878. Epub 2024 Oct 14. Cell Rep Methods. 2024. PMID: 39406231 Free PMC article.

7

Reduced function of the adaptor SH2B3 promotes T1D via altered gc cytokine-regulated, T cell intrinsic immune tolerance.

Watson TK, Rosen ABI, Drow T, Medjo JA, MacQuivey MA, Ge Y, Liggitt HD, Grosvenor DA, Dill-McFarland KA, Altman MC, Concannon PJ, Buckner JH, Rawlings DJ, Allenspach EJ. Watson TK, et al. Among authors: rawlings dj. bioRxiv [Preprint]. 2024 Aug 6:2024.08.02.606362. doi: 10.1101/2024.08.02.606362. bioRxiv. 2024. PMID: 39211124 Free PMC article. Preprint.

8

Blunting specific T-dependent antibody responses with engineered "decoy" B cells.

Pitner RA, Chao JL, Dahl NP, Fan MN, Cai X, Avery NG, Roe K, Spiegel PC Jr, Miao CH, Gerner MY, James RG, Rawlings DJ. Pitner RA, et al. Among authors: rawlings dj. Mol Ther. 2024 Oct 2;32(10):3453-3469. doi: 10.1016/j.ymthe.2024.08.023. Epub 2024 Aug 26. Mol Ther. 2024. PMID: 39192583

9

Human plasma cells engineered to secrete bispecifics drive effective in vivo leukemia killing.

Hill TF, Narvekar P, Asher GD, Edelstein JN, Camp ND, Grimm A, Thomas KR, Leiken MD, Molloy KM, Cook PJ, Arlauckas SP, Morgan RA, Tasian SK, Rawlings DJ, James RG. Hill TF, et al. Among authors: rawlings dj. Mol Ther. 2024 Aug 7;32(8):2676-2691. doi: 10.1016/j.ymthe.2024.06.004. Epub 2024 Jul 2. Mol Ther. 2024. PMID: 38959896

10

Activated PI3Kδ Specifically Perturbs Mouse Regulatory T Cell Homeostasis and Function Leading to Immune Dysregulation.

Singh AK, Al Qureshah F, Drow T, Hou B, Rawlings DJ. Singh AK, et al. Among authors: rawlings dj. J Immunol. 2024 Jul 15;213(2):135-147. doi: 10.4049/jimmunol.2400032. J Immunol. 2024. PMID: 38829130

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