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Rewiring of RNA methylation by the oncometabolite fumarate in renal cell carcinoma.
Fitzsimmons CM, Mandler MD, Lunger JC, Chan D, Maligireddy SS, Schmiechen AC, Gamage ST, Link C, Jenkins LM, Chan K, Andresson T, Crooks DR, Meier JL, Linehan WM, Batista PJ. Fitzsimmons CM, et al. Among authors: chan d, chan k. NAR Cancer. 2024 Feb 7;6(1):zcae004. doi: 10.1093/narcan/zcae004. eCollection 2024 Mar. NAR Cancer. 2024. PMID: 38328795 Free PMC article.
A Phase II Trial of Guadecitabine in Children and Adults with SDH-Deficient GIST, Pheochromocytoma, Paraganglioma, and HLRCC-Associated Renal Cell Carcinoma.
Ligon JA, Sundby RT, Wedekind MF, Arnaldez FI, Del Rivero J, Wiener L, Srinivasan R, Spencer M, Carbonell A, Lei H, Shern J, Steinberg SM, Figg WD, Peer CJ, Zimmerman S, Moraly J, Xu X, Fox S, Chan K, Barbato MI, Andresson T, Taylor N, Pacak K, Killian JK, Dombi E, Linehan WM, Miettinen M, Piekarz R, Helman LJ, Meltzer P, Widemann B, Glod J. Ligon JA, et al. Among authors: chan k. Clin Cancer Res. 2023 Jan 17;29(2):341-348. doi: 10.1158/1078-0432.CCR-22-2168. Clin Cancer Res. 2023. PMID: 36302175 Free PMC article. Clinical Trial.
Structure-guided bifunctional molecules hit a DEUBAD-lacking hRpn13 species upregulated in multiple myeloma.
Lu X, Sabbasani VR, Osei-Amponsa V, Evans CN, King JC, Tarasov SG, Dyba M, Das S, Chan KC, Schwieters CD, Choudhari S, Fromont C, Zhao Y, Tran B, Chen X, Matsuo H, Andresson T, Chari R, Swenson RE, Tarasova NI, Walters KJ. Lu X, et al. Nat Commun. 2021 Dec 16;12(1):7318. doi: 10.1038/s41467-021-27570-4. Nat Commun. 2021. PMID: 34916494 Free PMC article.
A novel retinoic acid receptor-γ agonist antagonizes immune checkpoint resistance in lung cancers by altering the tumor immune microenvironment.
Wei CH, Huang L, Kreh B, Liu X, Tyutyunyk-Massey L, Kawakami M, Chen Z, Shi M, Kozlov S, Chan KC, Andresson T, Carrington M, Vuligonda V, Sanders ME, Horowitz A, Hwu P, Peng W, Dmitrovsky E, Liu X. Wei CH, et al. Sci Rep. 2023 Sep 9;13(1):14907. doi: 10.1038/s41598-023-41690-5. Sci Rep. 2023. PMID: 37689790 Free PMC article.
Practice patterns and predictors of treatment intensification in patients with metastatic castration-sensitive prostate cancer.
Gotto GT, Yip SM, Shayegan B, O'Sullivan DE, Wallis CJD, Basappa NS, Cagiannos I, Hamilton RJ, Ferrario C, Fernandes R, Danielson B, Saad F, Hotte SJ, Cheung WY, Boyne DJ, Chan K, Osborne B, Zardan A, Malone S. Gotto GT, et al. Among authors: chan k. Can Urol Assoc J. 2024 Aug 30. doi: 10.5489/cuaj.8691. Online ahead of print. Can Urol Assoc J. 2024. PMID: 39470659 Free article.
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