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Regression-based Deep-Learning predicts molecular biomarkers from pathology slides.
El Nahhas OSM, Loeffler CML, Carrero ZI, van Treeck M, Kolbinger FR, Hewitt KJ, Muti HS, Graziani M, Zeng Q, Calderaro J, Ortiz-Brüchle N, Yuan T, Hoffmeister M, Brenner H, Brobeil A, Reis-Filho JS, Kather JN. El Nahhas OSM, et al. Among authors: loeffler cml. Nat Commun. 2024 Feb 10;15(1):1253. doi: 10.1038/s41467-024-45589-1. Nat Commun. 2024. PMID: 38341402 Free PMC article.
An overview and a roadmap for artificial intelligence in hematology and oncology.
Rösler W, Altenbuchinger M, Baeßler B, Beissbarth T, Beutel G, Bock R, von Bubnoff N, Eckardt JN, Foersch S, Loeffler CML, Middeke JM, Mueller ML, Oellerich T, Risse B, Scherag A, Schliemann C, Scholz M, Spang R, Thielscher C, Tsoukakis I, Kather JN. Rösler W, et al. Among authors: loeffler cml. J Cancer Res Clin Oncol. 2023 Aug;149(10):7997-8006. doi: 10.1007/s00432-023-04667-5. Epub 2023 Mar 15. J Cancer Res Clin Oncol. 2023. PMID: 36920563 Free PMC article. Review.
Automated curation of large-scale cancer histopathology image datasets using deep learning.
Hilgers L, Ghaffari Laleh N, West NP, Westwood A, Hewitt KJ, Quirke P, Grabsch HI, Carrero ZI, Matthaei E, Loeffler CML, Brinker TJ, Yuan T, Brenner H, Brobeil A, Hoffmeister M, Kather JN. Hilgers L, et al. Among authors: loeffler cml. Histopathology. 2024 Jun;84(7):1139-1153. doi: 10.1111/his.15159. Epub 2024 Feb 26. Histopathology. 2024. PMID: 38409878
Author Correction: Regression-based Deep-Learning predicts molecular biomarkers from pathology slides.
El Nahhas OSM, Loeffler CML, Carrero ZI, van Treeck M, Kolbinger FR, Hewitt KJ, Muti HS, Graziani M, Zeng Q, Calderaro J, Ortiz-Brüchle N, Yuan T, Hoffmeister M, Brenner H, Brobeil A, Reis-Filho JS, Kather JN. El Nahhas OSM, et al. Among authors: loeffler cml. Nat Commun. 2024 Feb 29;15(1):1868. doi: 10.1038/s41467-024-46298-5. Nat Commun. 2024. PMID: 38424093 Free PMC article. No abstract available.
Deep learning for dual detection of microsatellite instability and POLE mutations in colorectal cancer histopathology.
Gustav M, Reitsam NG, Carrero ZI, Loeffler CML, van Treeck M, Yuan T, West NP, Quirke P, Brinker TJ, Brenner H, Favre L, Märkl B, Stenzinger A, Brobeil A, Hoffmeister M, Calderaro J, Pujals A, Kather JN. Gustav M, et al. Among authors: loeffler cml. NPJ Precis Oncol. 2024 May 23;8(1):115. doi: 10.1038/s41698-024-00592-z. NPJ Precis Oncol. 2024. PMID: 38783059 Free PMC article.
Prediction of homologous recombination deficiency from routine histology with attention-based multiple instance learning in nine different tumor types.
Loeffler CML, El Nahhas OSM, Muti HS, Carrero ZI, Seibel T, van Treeck M, Cifci D, Gustav M, Bretz K, Gaisa NT, Lehmann KV, Leary A, Selenica P, Reis-Filho JS, Ortiz-Bruechle N, Kather JN. Loeffler CML, et al. BMC Biol. 2024 Oct 8;22(1):225. doi: 10.1186/s12915-024-02022-9. BMC Biol. 2024. PMID: 39379982 Free PMC article.
Prediction models for hormone receptor status in female breast cancer do not extend to males: further evidence of sex-based disparity in breast cancer.
Chatterji S, Niehues JM, van Treeck M, Loeffler CML, Saldanha OL, Veldhuizen GP, Cifci D, Carrero ZI, Abu-Eid R, Speirs V, Kather JN. Chatterji S, et al. Among authors: loeffler cml. NPJ Breast Cancer. 2023 Nov 8;9(1):91. doi: 10.1038/s41523-023-00599-y. NPJ Breast Cancer. 2023. PMID: 37940649 Free PMC article.
Direct prediction of Homologous Recombination Deficiency from routine histology in ten different tumor types with attention-based Multiple Instance Learning: a development and validation study.
Loeffler CML, El Nahhas OSM, Muti HS, Seibel T, Cifci D, van Treeck M, Gustav M, Carrero ZI, Gaisa NT, Lehmann KV, Leary A, Selenica P, Reis-Filho JS, Bruechle NO, Kather JN. Loeffler CML, et al. medRxiv [Preprint]. 2023 Mar 10:2023.03.08.23286975. doi: 10.1101/2023.03.08.23286975. medRxiv. 2023. Update in: BMC Biol. 2024 Oct 8;22(1):225. doi: 10.1186/s12915-024-02022-9 PMID: 36945540 Free PMC article. Updated. Preprint.
15 results