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Comparative analysis of KRAS4a and KRAS4b splice variants reveals distinctive structural and functional properties.
Whitley MJ, Tran TH, Rigby M, Yi M, Dharmaiah S, Waybright TJ, Ramakrishnan N, Perkins S, Taylor T, Messing S, Esposito D, Nissley DV, McCormick F, Stephen AG, Turbyville T, Cornilescu G, Simanshu DK. Whitley MJ, et al. Among authors: rigby m. Sci Adv. 2024 Feb 16;10(7):eadj4137. doi: 10.1126/sciadv.adj4137. Epub 2024 Feb 14. Sci Adv. 2024. PMID: 38354232 Free PMC article.
Membrane interactions of the globular domain and the hypervariable region of KRAS4b define its unique diffusion behavior.
Goswami D, Chen D, Yang Y, Gudla PR, Columbus J, Worthy K, Rigby M, Wheeler M, Mukhopadhyay S, Powell K, Burgan W, Wall V, Esposito D, Simanshu DK, Lightstone FC, Nissley DV, McCormick F, Turbyville T. Goswami D, et al. Among authors: rigby m. Elife. 2020 Jan 20;9:e47654. doi: 10.7554/eLife.47654. Elife. 2020. PMID: 31958057 Free PMC article.
RAS internal tandem duplication disrupts GTPase-activating protein (GAP) binding to activate oncogenic signaling.
Nelson AC, Turbyville TJ, Dharmaiah S, Rigby M, Yang R, Wang TY, Columbus J, Stephens R, Taylor T, Sciacca D, Onsongo G, Sarver A, Subramanian S, Nissley DV, Simanshu DK, Lou E. Nelson AC, et al. Among authors: rigby m. J Biol Chem. 2020 Jul 10;295(28):9335-9348. doi: 10.1074/jbc.RA119.011080. Epub 2020 May 11. J Biol Chem. 2020. PMID: 32393580 Free PMC article.
Virtual screening for small-molecule pathway regulators by image-profile matching.
Rohban MH, Fuller AM, Tan C, Goldstein JT, Syangtan D, Gutnick A, DeVine A, Nijsure MP, Rigby M, Sacher JR, Corsello SM, Peppler GB, Bogaczynska M, Boghossian A, Ciotti GE, Hands AT, Mekareeya A, Doan M, Gale JP, Derynck R, Turbyville T, Boerckel JD, Singh S, Kiessling LL, Schwarz TL, Varelas X, Wagner FF, Kafri R, Eisinger-Mathason TSK, Carpenter AE. Rohban MH, et al. Among authors: rigby m. Cell Syst. 2022 Sep 21;13(9):724-736.e9. doi: 10.1016/j.cels.2022.08.003. Epub 2022 Sep 2. Cell Syst. 2022. PMID: 36057257 Free PMC article.
Emissions of HFC-23 do not reflect commitments made under the Kigali Amendment.
Adam B, Western LM, Mühle J, Choi H, Krummel PB, O'Doherty S, Young D, Stanley KM, Fraser PJ, Harth CM, Salameh PK, Weiss RF, Prinn RG, Kim J, Park H, Park S, Rigby M. Adam B, et al. Among authors: rigby m. Commun Earth Environ. 2024;5(1):783. doi: 10.1038/s43247-024-01946-y. Epub 2024 Dec 21. Commun Earth Environ. 2024. PMID: 39717369 Free PMC article.
A trafficking regulatory subnetwork governs αVβ6 integrin-HER2 cross-talk to control breast cancer invasion and drug resistance.
Maldonado H, Dreger M, Bedgood LD, Kyriakou T, Wolanska KI, Rigby ME, Marotta VE, Webster JM, Wang J, Rusilowicz-Jones EV, Marshall JF, Coulson JM, Macpherson IR, Hurlstone A, Morgan MR. Maldonado H, et al. Among authors: rigby me. Sci Adv. 2024 Dec 6;10(49):eadk9944. doi: 10.1126/sciadv.adk9944. Epub 2024 Dec 4. Sci Adv. 2024. PMID: 39630893 Free PMC article.
645 results