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Structure- and machine learning-guided engineering demonstrate that a non-canonical disulfide in an anti-PD-1 rabbit antibody does not impede antibody developability.
Liang WC, Xi H, Sun D, D'Ascenzo L, Zarzar J, Stephens N, Cook R, Li Y, Ye Z, Matsumoto M, Payandeh J, Masureel M, Wu Y. Liang WC, et al. Among authors: ye z. MAbs. 2024 Jan-Dec;16(1):2309685. doi: 10.1080/19420862.2024.2309685. Epub 2024 Feb 14. MAbs. 2024. PMID: 38356181 Free PMC article.
Membrane-Proximal Epitope Facilitates Efficient T Cell Synapse Formation by Anti-FcRH5/CD3 and Is a Requirement for Myeloma Cell Killing.
Li J, Stagg NJ, Johnston J, Harris MJ, Menzies SA, DiCara D, Clark V, Hristopoulos M, Cook R, Slaga D, Nakamura R, McCarty L, Sukumaran S, Luis E, Ye Z, Wu TD, Sumiyoshi T, Danilenko D, Lee GY, Totpal K, Ellerman D, Hötzel I, James JR, Junttila TT. Li J, et al. Among authors: ye z. Cancer Cell. 2017 Mar 13;31(3):383-395. doi: 10.1016/j.ccell.2017.02.001. Epub 2017 Mar 2. Cancer Cell. 2017. PMID: 28262555 Free PMC article.
Extracellular BMP1 is the major proteinase for COOH-terminal proteolysis of type I procollagen in lung fibroblasts.
N'Diaye EN, Cook R, Wang H, Wu P, LaCanna R, Wu C, Ye Z, Seshasayee D, Hazen M, Lin W, Tyagi T, Hotzel I, Tam L, Newman R, Roose-Girma M, Wolters PJ, Ding N. N'Diaye EN, et al. Among authors: ye z. Am J Physiol Cell Physiol. 2021 Feb 1;320(2):C162-C174. doi: 10.1152/ajpcell.00012.2020. Epub 2020 Nov 18. Am J Physiol Cell Physiol. 2021. PMID: 33206546 Free article.
Using a peptide-based mass spectrometry approach to quantitate proteolysis of an intact heterogeneous procollagen substrate by BMP1 for antagonistic antibody screening.
Wu C, Cook R, Wu P, Srikumar N, Chee E, Sawyer WS, Wang H, Hazen M, Hotzel I, N'Diaye EN, Ding N, Liu Y, Tran JC, Ye Z. Wu C, et al. Among authors: ye z. Anal Bioanal Chem. 2022 Sep;414(22):6601-6610. doi: 10.1007/s00216-022-04220-2. Epub 2022 Jul 12. Anal Bioanal Chem. 2022. PMID: 35821276
Homeostatic functions of monocytes and interstitial lung macrophages are regulated via collagen domain-binding receptor LAIR1.
Keerthivasan S, Şenbabaoğlu Y, Martinez-Martin N, Husain B, Verschueren E, Wong A, Yang YA, Sun Y, Pham V, Hinkle T, Oei Y, Madireddi S, Corpuz R, Tam L, Carlisle S, Roose-Girma M, Modrusan Z, Ye Z, Koerber JT, Turley SJ. Keerthivasan S, et al. Among authors: ye z. Immunity. 2021 Jul 13;54(7):1511-1526.e8. doi: 10.1016/j.immuni.2021.06.012. Immunity. 2021. PMID: 34260887 Free article.
Gallstones, cholecystectomy, and cancer risk: an observational and Mendelian randomization study.
Zhu Y, Shen L, Huo Y, Wan Q, Qin Y, Hu R, Shi L, Su Q, Yu X, Yan L, Qin G, Tang X, Chen G, Xu Y, Wang T, Zhao Z, Gao Z, Wang G, Shen F, Gu X, Luo Z, Chen L, Li Q, Ye Z, Zhang Y, Liu C, Wang Y, Wu S, Yang T, Deng H, Chen L, Zeng T, Zhao J, Mu Y, Wang W, Ning G, Lu J, Xu M, Bi Y, Hu W. Zhu Y, et al. Among authors: ye z. Front Med. 2024 Dec 26. doi: 10.1007/s11684-024-1111-5. Online ahead of print. Front Med. 2024. PMID: 39722067
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