Huh Y - Search Results

1

Moving Beyond Boundaries: Utilization of Longitudinal Exposure-Response Model for Bounded Outcome Score to Inform Decision Making in the Accelerated Drug Development Paradigm.

Huh Y, Wojciechowski J, Purohit VS. Huh Y, et al. Clin Pharmacokinet. 2024 Mar;63(3):381-394. doi: 10.1007/s40262-024-01347-6. Epub 2024 Feb 15. Clin Pharmacokinet. 2024. PMID: 38358645 Free PMC article.

2

Evaluation of the Impact of Ritlecitinib on Organic Cation Transporters Using Sumatriptan and Biomarkers as Probes.

Wang X, Purohit V, Dowty ME, Rodrigues D, Luo L, Mathialagan S, Carey W, Plotka A, Kalluru H, Melissa O, Kaplan J, Huh Y, Vourvahis M, Wolk RM. Wang X, et al. Among authors: huh y. J Clin Pharmacol. 2023 Jul;63(7):784-797. doi: 10.1002/jcph.2215. Epub 2023 Apr 5. J Clin Pharmacol. 2023. PMID: 36807251

3

Leveraging Prior Healthy Participant Pharmacokinetic Data to Evaluate the Impact of Renal and Hepatic Impairment on Ritlecitinib Pharmacokinetics.

Purohit V, Huh Y, Wojciechowski J, Plotka A, Salts S, Antinew J, Dimitrova A, Nicholas T. Purohit V, et al. Among authors: huh y. AAPS J. 2023 Mar 28;25(3):32. doi: 10.1208/s12248-023-00792-8. AAPS J. 2023. PMID: 36977960 Free PMC article.

4

Utilization of Rosuvastatin and Endogenous Biomarkers in Evaluating the Impact of Ritlecitinib on BCRP, OATP1B1, and OAT3 Transporter Activity.

Huh Y, Plotka A, Wei H, Kaplan J, Raha N, Towner J, Purohit VS, Dowty ME, Wolk R, Vourvahis M, King-Ahmad A, Mathialagan S, West MA, Lazzaro S, Ryu S, Rodrigues AD. Huh Y, et al. Pharm Res. 2023 Nov;40(11):2639-2651. doi: 10.1007/s11095-023-03564-3. Epub 2023 Aug 10. Pharm Res. 2023. PMID: 37561322 Free PMC article.

5

Evolution of Ritlecitinib Population Pharmacokinetic Models During Clinical Drug Development.

Wojciechowski J, S Purohit V, Huh Y, Banfield C, Nicholas T. Wojciechowski J, et al. Among authors: huh y. Clin Pharmacokinet. 2023 Dec;62(12):1765-1779. doi: 10.1007/s40262-023-01318-3. Epub 2023 Nov 2. Clin Pharmacokinet. 2023. PMID: 37917289 Free PMC article.

6

Virtual Bioequivalence Assessment of Ritlecitinib Capsules with Incorporation of Observed Clinical Variability Using a Physiologically Based Pharmacokinetic Model.

Saadeddin A, Purohit V, Huh Y, Wong M, Maulny A, Dowty ME, Sagawa K. Saadeddin A, et al. Among authors: huh y. AAPS J. 2024 Jan 24;26(1):17. doi: 10.1208/s12248-024-00888-9. AAPS J. 2024. PMID: 38267790

7

Correction: Virtual Bioequivalence Assessment of Ritlecitinib Capsules with Incorporation of Observed Clinical Variability Using a Physiologically Based Pharmacokinetic Model.

Saadeddin A, Purohit V, Huh Y, Wong M, Maulny A, Dowty ME, Sagawa K. Saadeddin A, et al. Among authors: huh y. AAPS J. 2024 Feb 21;26(2):27. doi: 10.1208/s12248-024-00895-w. AAPS J. 2024. PMID: 38383803 No abstract available.

8

More Than a Gut Feeling─A Combination of Physiologically Driven Dissolution and Pharmacokinetic Modeling as a Tool for Understanding Human Gastric Motility.

Romański M, Staniszewska M, Dobosz J, Myslitska D, Paszkowska J, Kołodziej B, Romanova S, Banach G, Garbacz G, Sarcevica I, Huh Y, Purohit V, McAllister M, Wong SM, Danielak D. Romański M, et al. Among authors: huh y. Mol Pharm. 2024 Aug 5;21(8):3824-3837. doi: 10.1021/acs.molpharmaceut.4c00117. Epub 2024 Jul 3. Mol Pharm. 2024. PMID: 38958668 Free PMC article.

9

Assessment of the Effects of Abrocitinib on the Pharmacokinetics of Probe Substrates of Cytochrome P450 1A2, 2B6 and 2C19 Enzymes and Hormonal Oral Contraceptives in Healthy Individuals.

Wang X, Dowty ME, Tripathy S, Le VH, Huh Y, Curto M, Winton JA, O'Gorman MT, Chan G, Malhotra BK. Wang X, et al. Among authors: huh y. Eur J Drug Metab Pharmacokinet. 2024 May;49(3):367-381. doi: 10.1007/s13318-024-00893-5. Epub 2024 Mar 30. Eur J Drug Metab Pharmacokinet. 2024. PMID: 38554232 Free PMC article. Clinical Trial.

10

Population exposure-response analysis of the effect of ritlecitinib on eyebrow assessment and eyelash assessment in patients with alopecia areata.

Wang Y, Huh Y, Lejeune A. Wang Y, et al. Among authors: huh y. CPT Pharmacometrics Syst Pharmacol. 2025 Jan 15. doi: 10.1002/psp4.13283. Online ahead of print. CPT Pharmacometrics Syst Pharmacol. 2025. PMID: 39812118 Free article.

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