LeHoux D - Search Results

1

The Engineered Lysin CF-370 Is Active Against Antibiotic-Resistant Gram-Negative Pathogens In Vitro and Synergizes With Meropenem in Experimental Pseudomonas aeruginosa Pneumonia.

Sauve K, Watson A, Oh JT, Swift S, Vila-Farres X, Abdelhady W, Xiong YQ, LeHoux D, Woodnutt G, Bayer AS, Schuch R. Sauve K, et al. Among authors: lehoux d. J Infect Dis. 2024 Aug 16;230(2):309-318. doi: 10.1093/infdis/jiae027. J Infect Dis. 2024. PMID: 38366561

2

In vitro activity of exebacase against methicillin-resistant Staphylococcus aureus biofilms on orthopedic Kirschner wires.

Karau MJ, Mandrekar J, Lehoux D, Schuch R, Cassino C, Patel R. Karau MJ, et al. Among authors: lehoux d. BMC Res Notes. 2023 Sep 11;16(1):209. doi: 10.1186/s13104-023-06468-y. BMC Res Notes. 2023. PMID: 37697424 Free PMC article.

3

The N-Acetylgalactosamine-conjugated small interfering RNA inclisiran can be coadministered safely with atorvastatin in cynomolgus monkeys resulting in additive low-density lipoprotein cholesterol reductions.

Lehoux D, Kallend D, Wijngaard PLJ, Brown AP, Zerler B. Lehoux D, et al. Pharmacol Res Perspect. 2023 Apr;11(2):e01080. doi: 10.1002/prp2.1080. Pharmacol Res Perspect. 2023. PMID: 37021909 Free PMC article.

4

Disease versus disease: Paolo Zacchia on syphilis and epilepsy.

Duffin J, Lehoux D. Duffin J, et al. Among authors: lehoux d. J Med Biogr. 2024 May;32(2):248-256. doi: 10.1177/09677720221129856. Epub 2022 Dec 13. J Med Biogr. 2024. PMID: 36514299 Free PMC article.

5

Locally delivered antistaphylococcal lysin exebacase or CF-296 is active in methicillin-resistant Staphylococcus aureus implant-associated osteomyelitis.

Karau M, Schmidt-Malan S, Mandrekar J, Lehoux D, Schuch R, Cassino C, Patel R. Karau M, et al. Among authors: lehoux d. J Bone Jt Infect. 2022 Jul 27;7(4):169-175. doi: 10.5194/jbji-7-169-2022. eCollection 2022. J Bone Jt Infect. 2022. PMID: 36032801 Free PMC article.

6

Corrigendum to "Evaluation of the distribution and excretion of [¹⁴C]-inclisiran following single subcutaneous administration in cynomolgus monkeys" [Toxicology and Applied Pharmacology 443 (2022) 115978].

Lehoux D, Far AR, Kallend D, Wijngaard PLJ, Zerler B. Lehoux D, et al. Toxicol Appl Pharmacol. 2022 Sep 15;451:116144. doi: 10.1016/j.taap.2022.116144. Epub 2022 Jul 1. Toxicol Appl Pharmacol. 2022. PMID: 35780943 No abstract available.

7

Evaluation of the distribution and excretion of [¹⁴C]-inclisiran following single subcutaneous administration in cynomolgus monkeys.

Lehoux D, Far AR, Kallend D, Wijngaard PLJ, Zerler B. Lehoux D, et al. Toxicol Appl Pharmacol. 2022 May 15;443:115978. doi: 10.1016/j.taap.2022.115978. Epub 2022 Mar 11. Toxicol Appl Pharmacol. 2022. PMID: 35288146

8

Exebacase in Addition to Daptomycin against MRSA.

Kebriaei R, Stamper KC, Lev KL, Morrisette T, Abdul-Mutakabbir JC, Schuch R, Lehoux D, Rybak MJ. Kebriaei R, et al. Among authors: lehoux d. Antimicrob Agents Chemother. 2021 Oct 18;65(11):e0012821. doi: 10.1128/AAC.00128-21. Epub 2021 Aug 16. Antimicrob Agents Chemother. 2021. PMID: 34398668 Free PMC article.

9

Efficacy assessment of lysin CF-296 in addition to daptomycin or vancomycin against Staphylococcus aureus in the murine thigh infection model.

Asempa TE, DeRosa NA, Cassino C, Lehoux D, Schuch R, Nicolau DP. Asempa TE, et al. Among authors: lehoux d. J Antimicrob Chemother. 2021 Sep 15;76(10):2622-2628. doi: 10.1093/jac/dkab206. J Antimicrob Chemother. 2021. PMID: 34223628

10

Activity of Lysin CF-296 Alone and in Addition to Daptomycin in a Rat Model of Experimental Methicillin-Resistant Staphylococcus aureus Osteomyelitis.

Karau MJ, Schmidt-Malan SM, Mandrekar J, Lehoux D, Schuch R, Cassino C, Patel R. Karau MJ, et al. Among authors: lehoux d. Antimicrob Agents Chemother. 2021 May 18;65(6):e00117-21. doi: 10.1128/AAC.00117-21. Print 2021 May 18. Antimicrob Agents Chemother. 2021. PMID: 33722889 Free PMC article. No abstract available.

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