Schuch R - Search Results

1

The Engineered Lysin CF-370 Is Active Against Antibiotic-Resistant Gram-Negative Pathogens In Vitro and Synergizes With Meropenem in Experimental Pseudomonas aeruginosa Pneumonia.

Sauve K, Watson A, Oh JT, Swift S, Vila-Farres X, Abdelhady W, Xiong YQ, LeHoux D, Woodnutt G, Bayer AS, Schuch R. Sauve K, et al. Among authors: schuch r. J Infect Dis. 2024 Aug 16;230(2):309-318. doi: 10.1093/infdis/jiae027. J Infect Dis. 2024. PMID: 38366561

2

Combination therapy with lysin CF-301 and antibiotic is superior to antibiotic alone for treating methicillin-resistant Staphylococcus aureus-induced murine bacteremia.

Schuch R, Lee HM, Schneider BC, Sauve KL, Law C, Khan BK, Rotolo JA, Horiuchi Y, Couto DE, Raz A, Fischetti VA, Huang DB, Nowinski RC, Wittekind M. Schuch R, et al. J Infect Dis. 2014 May 1;209(9):1469-78. doi: 10.1093/infdis/jit637. Epub 2013 Nov 28. J Infect Dis. 2014. PMID: 24286983 Free PMC article.

3

The Antistaphylococcal Lysin, CF-301, Activates Key Host Factors in Human Blood To Potentiate Methicillin-Resistant Staphylococcus aureus Bacteriolysis.

Indiani C, Sauve K, Raz A, Abdelhady W, Xiong YQ, Cassino C, Bayer AS, Schuch R. Indiani C, et al. Among authors: schuch r. Antimicrob Agents Chemother. 2019 Mar 27;63(4):e02291-18. doi: 10.1128/AAC.02291-18. Print 2019 Apr. Antimicrob Agents Chemother. 2019. PMID: 30670427 Free PMC article.

4

Postantibiotic and Sub-MIC Effects of Exebacase (Lysin CF-301) Enhance Antimicrobial Activity against Staphylococcus aureus.

Oh JT, Cassino C, Schuch R. Oh JT, et al. Among authors: schuch r. Antimicrob Agents Chemother. 2019 May 24;63(6):e02616-18. doi: 10.1128/AAC.02616-18. Print 2019 Jun. Antimicrob Agents Chemother. 2019. PMID: 30936103 Free PMC article.

5

Antimicrobial Activity of Exebacase (Lysin CF-301) against the Most Common Causes of Infective Endocarditis.

Watson A, Oh JT, Sauve K, Bradford PA, Cassino C, Schuch R. Watson A, et al. Among authors: schuch r. Antimicrob Agents Chemother. 2019 Sep 23;63(10):e01078-19. doi: 10.1128/AAC.01078-19. Print 2019 Oct. Antimicrob Agents Chemother. 2019. PMID: 31332073 Free PMC article.

6

In vitro activity of Exebacase (CF-301) against clinical Staphylococcus aureus surveillance isolates from the United States, Europe, and Latin America, 2015-2017.

Traczewski M, Oh J, Cassino C, Schuch R. Traczewski M, et al. Among authors: schuch r. Diagn Microbiol Infect Dis. 2019 Dec;95(4):114879. doi: 10.1016/j.diagmicrobio.2019.114879. Epub 2019 Aug 1. Diagn Microbiol Infect Dis. 2019. PMID: 31466875

7

Exebacase Demonstrates In Vitro Synergy with a Broad Range of Antibiotics against both Methicillin-Resistant and Methicillin-Susceptible Staphylococcus aureus.

Watson A, Sauve K, Cassino C, Schuch R. Watson A, et al. Among authors: schuch r. Antimicrob Agents Chemother. 2020 Jan 27;64(2):e01885-19. doi: 10.1128/AAC.01885-19. Print 2020 Jan 27. Antimicrob Agents Chemother. 2020. PMID: 31712212 Free PMC article.

8

Effect of the Lysin Exebacase on Cardiac Vegetation Progression in a Rabbit Model of Methicillin-Resistant Staphylococcus aureus Endocarditis as Determined by Echocardiography.

Shah SU, Xiong YQ, Abdelhady W, Iwaz J, Pak Y, Schuch R, Cassino C, Lehoux D, Bayer AS. Shah SU, et al. Among authors: schuch r. Antimicrob Agents Chemother. 2020 Jun 23;64(7):e00482-20. doi: 10.1128/AAC.00482-20. Print 2020 Jun 23. Antimicrob Agents Chemother. 2020. PMID: 32340988 Free PMC article.

9

Exebacase Is Active In Vitro in Pulmonary Surfactant and Is Efficacious Alone and Synergistic with Daptomycin in a Mouse Model of Lethal Staphylococcus aureus Lung Infection.

Swift SM, Sauve K, Cassino C, Schuch R. Swift SM, et al. Among authors: schuch r. Antimicrob Agents Chemother. 2021 Aug 17;65(9):e0272320. doi: 10.1128/AAC.02723-20. Epub 2021 Aug 17. Antimicrob Agents Chemother. 2021. PMID: 34228536 Free PMC article.

10

Direct Lytic Agents: Novel, Rapidly Acting Potential Antimicrobial Treatment Modalities for Systemic Use in the Era of Rising Antibiotic Resistance.

Schuch R, Cassino C, Vila-Farres X. Schuch R, et al. Front Microbiol. 2022 Mar 3;13:841905. doi: 10.3389/fmicb.2022.841905. eCollection 2022. Front Microbiol. 2022. PMID: 35308352 Free PMC article. Review.

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