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19 results

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Page 1
Efficacy and Safety of Filgotinib for the Treatment of Perianal Fistulising Crohn's Disease [DIVERGENCE 2]: A Phase 2, Randomised, Placebo-controlled Trial.
Reinisch W, Colombel JF, D'Haens GR, Rimola J, Masior T, McKevitt M, Ren X, Serone A, Schwartz DA, Gecse KB. Reinisch W, et al. Among authors: serone a. J Crohns Colitis. 2024 Jun 3;18(6):864-874. doi: 10.1093/ecco-jcc/jjae003. J Crohns Colitis. 2024. PMID: 38366672 Free PMC article. Clinical Trial.
Filgotinib for the Treatment of Small Bowel Crohn's Disease: The DIVERGENCE 1 Trial.
D'Haens GR, Lee S, Taylor SA, Serone A, Rimola J, Colombel JF; DIVERGENCE 1 Study Group. D'Haens GR, et al. Among authors: serone a. Gastroenterology. 2023 Jul;165(1):289-292.e3. doi: 10.1053/j.gastro.2023.03.234. Epub 2023 Apr 11. Gastroenterology. 2023. PMID: 37054757 Free article. No abstract available.
Mucosal p-STAT1/3 correlates with histologic disease activity in Crohn's disease and is responsive to filgotinib.
Reinisch W, Serone A, Hébuterne X, Kühbacher T, Kłopocka M, Roblin X, Brodbeck J, Etchevers K, Galien R, Grant E, Tasset C, Yoon OK, Zaboli S, Vermeire S. Reinisch W, et al. Among authors: serone a. Tissue Barriers. 2023 Apr 3;11(2):2088961. doi: 10.1080/21688370.2022.2088961. Epub 2022 Jun 28. Tissue Barriers. 2023. PMID: 35762272 Free PMC article. Clinical Trial.
Safety, Pharmacokinetics, and Pharmacodynamics in Healthy Volunteers Treated With GDC-0853, a Selective Reversible Bruton's Tyrosine Kinase Inhibitor.
Herman AE, Chinn LW, Kotwal SG, Murray ER, Zhao R, Florero M, Lin A, Moein A, Wang R, Bremer M, Kokubu S, Serone AP, Hanze EL, Viberg A, Morimoto AM, Winter HR, Katsumoto TR. Herman AE, et al. Among authors: serone ap. Clin Pharmacol Ther. 2018 Jun;103(6):1020-1028. doi: 10.1002/cpt.1056. Epub 2018 Mar 23. Clin Pharmacol Ther. 2018. PMID: 29484638 Clinical Trial.
Novel anti-tumour necrosis factor receptor-1 (TNFR1) domain antibody prevents pulmonary inflammation in experimental acute lung injury.
Proudfoot A, Bayliffe A, O'Kane CM, Wright T, Serone A, Bareille PJ, Brown V, Hamid UI, Chen Y, Wilson R, Cordy J, Morley P, de Wildt R, Elborn S, Hind M, Chilvers ER, Griffiths M, Summers C, McAuley DF. Proudfoot A, et al. Among authors: serone a. Thorax. 2018 Aug;73(8):723-730. doi: 10.1136/thoraxjnl-2017-210305. Epub 2018 Jan 29. Thorax. 2018. PMID: 29382797 Free PMC article. Clinical Trial.
Efficacy and safety of an anti-IL-13 mAb in patients with severe asthma: a randomized trial.
De Boever EH, Ashman C, Cahn AP, Locantore NW, Overend P, Pouliquen IJ, Serone AP, Wright TJ, Jenkins MM, Panesar IS, Thiagarajah SS, Wenzel SE. De Boever EH, et al. Among authors: serone ap. J Allergy Clin Immunol. 2014 Apr;133(4):989-96. doi: 10.1016/j.jaci.2014.01.002. Epub 2014 Feb 28. J Allergy Clin Immunol. 2014. PMID: 24582316 Clinical Trial.
Autoantibodies to variable heavy (VH) chain Ig sequences in humans impact the safety and clinical pharmacology of a VH domain antibody antagonist of TNF-α receptor 1.
Holland MC, Wurthner JU, Morley PJ, Birchler MA, Lambert J, Albayaty M, Serone AP, Wilson R, Chen Y, Forrest RM, Cordy JC, Lipson DA, Bayliffe AI. Holland MC, et al. Among authors: serone ap. J Clin Immunol. 2013 Oct;33(7):1192-203. doi: 10.1007/s10875-013-9915-0. Epub 2013 Jul 6. J Clin Immunol. 2013. PMID: 23832582 Clinical Trial.
19 results