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Seminoma-a rare cause of a bleeding intra-abdominal mass.
Anderson C, Towers S, Cribb B, Vermeulen W. Anderson C, et al. Among authors: vermeulen w. ANZ J Surg. 2024 Apr;94(4):767-768. doi: 10.1111/ans.18908. Epub 2024 Feb 17. ANZ J Surg. 2024. PMID: 38366702 No abstract available.
CYP3A4-Mediated Bioactivation of the β-Amyloid Precursor Protein-Cleaving Enzyme 1 Inhibitor JNJ-54861911 Results in Redox-Neutral Addition of Glutathione via Catalysis by Glutathione S-Transferase α1, Identified as the Major Target Protein in Human Hepatocytes.
Leclercq L, de Vries R, Koppen V, Verboven P, Cuyckens F, Wynant I, Vermeulen WAA, Naisbitt D, Ford M, Meng X, Sakamoto S, Fukushima T, Snoeys J. Leclercq L, et al. Among authors: vermeulen waa. Chem Res Toxicol. 2024 Dec 11. doi: 10.1021/acs.chemrestox.4c00279. Online ahead of print. Chem Res Toxicol. 2024. PMID: 39662968
STK19 drives transcription-coupled repair by stimulating repair complex stability, RNA Pol II ubiquitylation, and TFIIH recruitment.
Ramadhin AR, Lee SH, Zhou D, Salmazo A, Gonzalo-Hansen C, van Sluis M, Blom CMA, Janssens RC, Raams A, Dekkers D, Bezstarosti K, Slade D, Vermeulen W, Pines A, Demmers JAA, Bernecky C, Sixma TK, Marteijn JA. Ramadhin AR, et al. Among authors: vermeulen w. Mol Cell. 2024 Dec 19;84(24):4740-4757.e12. doi: 10.1016/j.molcel.2024.10.030. Epub 2024 Nov 14. Mol Cell. 2024. PMID: 39547223 Free article.
The small CRL4CSA ubiquitin ligase component DDA1 regulates transcription-coupled repair dynamics.
Llerena Schiffmacher DA, Lee SH, Kliza KW, Theil AF, Akita M, Helfricht A, Bezstarosti K, Gonzalo-Hansen C, van Attikum H, Verlaan-de Vries M, Vertegaal ACO, Hoeijmakers JHJ, Marteijn JA, Lans H, Demmers JAA, Vermeulen M, Sixma TK, Ogi T, Vermeulen W, Pines A. Llerena Schiffmacher DA, et al. Among authors: vermeulen w. Nat Commun. 2024 Jul 29;15(1):6374. doi: 10.1038/s41467-024-50584-7. Nat Commun. 2024. PMID: 39075067 Free PMC article.
Skin Cancer Induction by the Antimycotic Drug Voriconazole Is Caused by Impaired DNA Damage Detection Due to Chromatin Compaction.
Giovannini S, Weibel L, Schittek B, Sinnberg T, Schaller M, Lemberg C, Fehrenbacher B, Biesemeier A, Nordin R, Ivanova I, Kurz B, Svilenska T, Berger C, Bourquin JP, Kulik A, Fassihi H, Lehmann A, Sarkany R, Kobert N, van Toorn M, Marteijn JA, French LE, Rocken M, Vermeulen W, Kamenisch Y, Berneburg M. Giovannini S, et al. Among authors: vermeulen w. J Invest Dermatol. 2024 Nov;144(11):2465-2476. doi: 10.1016/j.jid.2024.03.050. Epub 2024 Jul 22. J Invest Dermatol. 2024. PMID: 39047967
Persistent TFIIH binding to non-excised DNA damage causes cell and developmental failure.
Muniesa-Vargas A, Davó-Martínez C, Ribeiro-Silva C, van der Woude M, Thijssen KL, Haspels B, Häckes D, Kaynak ÜU, Kanaar R, Marteijn JA, Theil AF, Kuijten MMP, Vermeulen W, Lans H. Muniesa-Vargas A, et al. Among authors: vermeulen w. Nat Commun. 2024 Apr 25;15(1):3490. doi: 10.1038/s41467-024-47935-9. Nat Commun. 2024. PMID: 38664429 Free PMC article.
Transcription-coupled DNA-protein crosslink repair by CSB and CRL4CSA-mediated degradation.
van Sluis M, Yu Q, van der Woude M, Gonzalo-Hansen C, Dealy SC, Janssens RC, Somsen HB, Ramadhin AR, Dekkers DHW, Wienecke HL, Demmers JJPG, Raams A, Davó-Martínez C, Llerena Schiffmacher DA, van Toorn M, Häckes D, Thijssen KL, Zhou D, Lammers JG, Pines A, Vermeulen W, Pothof J, Demmers JAA, van den Berg DLC, Lans H, Marteijn JA. van Sluis M, et al. Among authors: vermeulen w. Nat Cell Biol. 2024 May;26(5):770-783. doi: 10.1038/s41556-024-01394-y. Epub 2024 Apr 10. Nat Cell Biol. 2024. PMID: 38600236 Free PMC article.
238 results