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A SARS-CoV-2 RBD vaccine fused to the chemokine MIP-3α elicits sustained murine antibody responses over 12 months and enhanced lung T-cell responses.
Gordy JT, Hui Y, Schill C, Wang T, Chen F, Fessler K, Meza J, Li Y, Taylor AD, Bates RE, Karakousis PC, Pekosz A, Sachithanandham J, Li M, Karanika S, Markham RB. Gordy JT, et al. Among authors: karakousis pc. Front Immunol. 2024 Feb 2;15:1292059. doi: 10.3389/fimmu.2024.1292059. eCollection 2024. Front Immunol. 2024. PMID: 38370404 Free PMC article.
The heme oxygenase-1 metalloporphyrin inhibitor stannsoporfin enhances the bactericidal activity of a novel regimen for multidrug-resistant tuberculosis in a murine model.
Castillo JR, Neupane P, Karanika S, Krug S, Quijada D, Garcia A, Ayeh S, Yilma A, Costa DL, Sher A, Fotouhi N, Serbina N, Karakousis PC. Castillo JR, et al. Among authors: karakousis pc. bioRxiv [Preprint]. 2023 Nov 13:2023.08.09.552716. doi: 10.1101/2023.08.09.552716. bioRxiv. 2023. Update in: Antimicrob Agents Chemother. 2024 Feb 7;68(2):e0104323. doi: 10.1128/aac.01043-23 PMID: 37609351 Free PMC article. Updated. Preprint.
Therapeutic DNA Vaccine Targeting Mycobacterium tuberculosis Persisters Shortens Curative Tuberculosis Treatment.
Karanika S, Wang T, Yilma A, Castillo JR, Gordy JT, Bailey H, Quijada D, Fessler K, Tasneen R, Rouse Salcido EM, Harris HT, Bates RE, Ton H, Meza J, Li Y, Taylor AD, Zheng JJ, Zhang J, Peske JD, Karantanos T, Maxwell AR, Nuermberger E, Markham RB, Karakousis PC. Karanika S, et al. Among authors: karakousis pc. bioRxiv [Preprint]. 2024 Sep 7:2024.09.03.611055. doi: 10.1101/2024.09.03.611055. bioRxiv. 2024. PMID: 39282461 Free PMC article. Preprint.
Targeting CCRL2 enhances therapeutic outcomes in a tuberculosis mouse model.
Wang T, Quijada D, Ahmenda T, Castillo JR, Naji NS, Peske JD, Karakousis PC, Paul S, Karantanos T, Karanika S. Wang T, et al. Among authors: karakousis pc. bioRxiv [Preprint]. 2024 Sep 25:2024.09.23.614576. doi: 10.1101/2024.09.23.614576. bioRxiv. 2024. PMID: 39386470 Free PMC article. Preprint.
Brief Communication: Combination of an MIP3α-Antigen Fusion Therapeutic DNA Vaccine With Treatments of IFNα and 5-Aza-2'Deoxycytidine Enhances Activated Effector CD8+ T Cells Expressing CD11c in the B16F10 Melanoma Model.
Fessler K, Zhang J, Sandhu AK, Hui Y, Kapoor AR, Ayeh SK, Karanika S, Karakousis PC, Markham RB, Gordy JT. Fessler K, et al. Among authors: karakousis pc. J Immunother. 2025 Jan 1;48(1):1-5. doi: 10.1097/CJI.0000000000000542. Epub 2024 Oct 14. J Immunother. 2025. PMID: 39397434
Sex differences in lung imaging and SARS-CoV-2 antibody responses in a COVID-19 golden Syrian hamster model.
Dhakal S, Ruiz-Bedoya CA, Zhou R, Creisher P, Villano J, Littlefield K, Castillo J, Marinho P, Jedlicka A, Ordonez A, Majewska N, Betenbaugh M, Flavahan K, Mueller A, Looney M, Quijada D, Mota F, Beck SE, Brockhurst JK, Braxton A, Castell N, D'Alessio F, Metcalf Pate KA, Karakousis PC, Mankowski JL, Pekosz A, Jain SK, Klein SL. Dhakal S, et al. Among authors: karakousis pc. bioRxiv [Preprint]. 2021 Apr 4:2021.04.02.438292. doi: 10.1101/2021.04.02.438292. bioRxiv. 2021. Update in: mBio. 2021 Aug 31;12(4):e0097421. doi: 10.1128/mBio.00974-21 PMID: 33821269 Free PMC article. Updated. Preprint.
Pharmacological inhibition of macrophage triglyceride biosynthesis pathways does not improve Mycobacterium tuberculosis control in infected mice.
Ruelas Castillo J, Guerrini V, Quijada D, Karanika S, Neupane P, Urbanowski ME, Shenkoya B, Harris H, Garcia A, Yilma A, Annunziata H, Khan R, Gopalakrishnan M, Gennaro ML, Karakousis PC. Ruelas Castillo J, et al. Among authors: karakousis pc. J Infect Dis. 2024 Nov 19:jiae577. doi: 10.1093/infdis/jiae577. Online ahead of print. J Infect Dis. 2024. PMID: 39560474
152 results