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A Chronic Increase in Blood-Brain Barrier Permeability Facilitates Intraneuronal Deposition of Exogenous Bloodborne Amyloid-Beta1-42 Peptide in the Brain and Leads to Alzheimer's Disease-Relevant Cognitive Changes in a Mouse Model.
Acharya NK, Grossman HC, Clifford PM, Levin EC, Light KR, Choi H, Swanson Ii RL, Kosciuk MC, Venkataraman V, Libon DJ, Matzel LD, Nagele RG. Acharya NK, et al. Among authors: kosciuk mc. J Alzheimers Dis. 2024;98(1):163-186. doi: 10.3233/JAD-231028. J Alzheimers Dis. 2024. PMID: 38393907 Free PMC article.
Diabetes and hypercholesterolemia increase blood-brain barrier permeability and brain amyloid deposition: beneficial effects of the LpPLA2 inhibitor darapladib.
Acharya NK, Levin EC, Clifford PM, Han M, Tourtellotte R, Chamberlain D, Pollaro M, Coretti NJ, Kosciuk MC, Nagele EP, Demarshall C, Freeman T, Shi Y, Guan C, Macphee CH, Wilensky RL, Nagele RG. Acharya NK, et al. Among authors: kosciuk mc. J Alzheimers Dis. 2013;35(1):179-98. doi: 10.3233/JAD-122254. J Alzheimers Dis. 2013. PMID: 23388174 Free article.
Sevoflurane and Isoflurane induce structural changes in brain vascular endothelial cells and increase blood-brain barrier permeability: Possible link to postoperative delirium and cognitive decline.
Acharya NK, Goldwaser EL, Forsberg MM, Godsey GA, Johnson CA, Sarkar A, DeMarshall C, Kosciuk MC, Dash JM, Hale CP, Leonard DM, Appelt DM, Nagele RG. Acharya NK, et al. Among authors: kosciuk mc. Brain Res. 2015 Sep 16;1620:29-41. doi: 10.1016/j.brainres.2015.04.054. Epub 2015 May 8. Brain Res. 2015. PMID: 25960348
Detection of Alzheimer's disease at mild cognitive impairment and disease progression using autoantibodies as blood-based biomarkers.
DeMarshall CA, Nagele EP, Sarkar A, Acharya NK, Godsey G, Goldwaser EL, Kosciuk M, Thayasivam U, Han M, Belinka B, Nagele RG; Alzheimer's Disease Neuroimaging Initiative. DeMarshall CA, et al. Alzheimers Dement (Amst). 2016 Apr 12;3:51-62. doi: 10.1016/j.dadm.2016.03.002. eCollection 2016. Alzheimers Dement (Amst). 2016. PMID: 27239548 Free PMC article.
Retinal pathology is associated with increased blood-retina barrier permeability in a diabetic and hypercholesterolaemic pig model: Beneficial effects of the LpPLA2 inhibitor Darapladib.
Acharya NK, Qi X, Goldwaser EL, Godsey GA, Wu H, Kosciuk MC, Freeman TA, Macphee CH, Wilensky RL, Venkataraman V, Nagele RG. Acharya NK, et al. Among authors: kosciuk mc. Diab Vasc Dis Res. 2017 May;14(3):200-213. doi: 10.1177/1479164116683149. Epub 2017 Mar 1. Diab Vasc Dis Res. 2017. PMID: 28301218 Free article.
24 results